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DNA Glycosylases (DNA Glycosylase)

A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.
Also Known As:
DNA Glycosylase; Methylpurine DNA Glycosylase; DNA Glycosylase, Methylpurine; DNA N glycosidase; Glycosylase, DNA; Glycosylase, Methylpurine DNA; Glycosylases, DNA; DNA N-glycosidase
Networked: 334 relevant articles (5 outcomes, 37 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Bjørås, Magnar: 16 articles (11/2021 - 06/2005)
2. Nakabeppu, Yusaku: 11 articles (01/2021 - 01/2002)
3. Zhang, Chun-Yang: 8 articles (01/2022 - 01/2016)
4. Luna, Luisa: 8 articles (11/2021 - 06/2005)
5. Bohr, Vilhelm A: 8 articles (01/2021 - 01/2005)
6. Suganthan, Rajikala: 8 articles (01/2021 - 11/2011)
7. Boldogh, Istvan: 7 articles (05/2022 - 09/2007)
8. Scheffler, Katja: 7 articles (11/2021 - 03/2012)
9. Aukrust, Pål: 6 articles (10/2021 - 06/2005)
10. Lloyd, R Stephen: 6 articles (01/2021 - 11/2004)

Related Diseases

1. Neoplasms (Cancer)
2. Bipolar Disorder (Manic Depressive Psychosis)
3. Pneumonia (Pneumonitis)
4. Ischemic Stroke
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. 8-hydroxyguanine
2. Proteins (Proteins, Gene)
3. Antioxidants
4. 8-Hydroxy-2'-Deoxyguanosine
5. DNA-(Apurinic or Apyrimidinic Site) Lyase (AP Endonuclease)
6. Carotenoids (Carotene)
7. Enzymes
8. DNA (Deoxyribonucleic Acid)
9. Endonucleases
10. DNA Repair Enzymes

Related Therapies and Procedures

1. Radiotherapy
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Quantum Dots (Quantum Dot)
5. Photochemotherapy (Photodynamic Therapy)