|3.||Cystic Fibrosis (Mucoviscidosis)
|4.||Exocrine Pancreatic Insufficiency
|1.||Walkowiak, Jaroslaw: 4 articles (03/2009 - 02/2005)|
|2.||Lui, Wing-Yiu: 4 articles (11/2007 - 06/2002)|
|3.||Shyr, Yi-Ming: 4 articles (11/2007 - 06/2002)|
|4.||Su, Cheng-Hsi: 4 articles (11/2007 - 06/2002)|
|5.||DiMagno, Eugene P: 3 articles (09/2012 - 12/2003)|
|6.||Wu, Chew-Wun: 3 articles (11/2007 - 06/2002)|
|7.||Herzig, Karl-Heinz: 3 articles (12/2006 - 02/2005)|
|8.||Carrière, Frédéric: 2 articles (12/2015 - 05/2005)|
|9.||Laugier, René: 2 articles (12/2015 - 05/2005)|
|10.||Stanga, Zeno: 2 articles (08/2015 - 02/2004)|
12/01/1993 - "Supplemental pancreatic enzymes resulted in marked improvement of steatorrhea. "
08/01/1994 - "The increased doses of pancreatic enzymes resulted in improved correction of steatorrhea."
01/01/2005 - "Overall, there was no steatorrhea in 92 (82.8%) patients after non-stented PPPD-PG, including 69 (62.2%) patients without replacement of pancreatic enzymes and 23 (20.7%) patients after replacement of pancreatic enzymes. "
01/01/1999 - "During the first days of OCT treatment, abdominal discomfort was referred by 12 patients and steatorrhea by 5 patients: side effects disappeared spontaneously in 6 cases while during treatment with pancreatic enzymes in the remaining ones. "
01/01/1991 - "These data suggest that large doses of EC enzymes reduce steatorrhea and are safe in patients who have malabsorbtion with small doses."
07/01/1984 - "Administration of medium chain triglycerides was uniformly effective in improving nutrition in patients with steatorrhea, but the course of the disease was unaffected. "
02/01/1986 - "Formulas with medium-chain triglycerides may be useful for infants with steatorrhea. "
11/01/1983 - "Of our control group 95% had a normal rise of triglycerides; and 96% of our patients with steatorrhea had an abnormal rise. "
03/01/1975 - "The effect of medium-chain triglycerides (MCT) on the "physiological" steatorrhea of prematurity was studied in 34 infants with birthweights below 2,000 gm. "
01/01/1971 - "Clinical and physiologic aspects of medium-chain triglycerides: allviation of steatorrhea in premature infants."
07/01/1989 - "[Efficacy of a new microencapsulated pancreatin versus a conventional preparation, in the treatment of steatorrhea of pancreatic origin]."
05/01/2013 - "Patients with steatorrhea, a pathological pancreatic function test, or clinical evidence of malabsorption should be given pancreatin supplementation. "
02/14/1986 - "[Effect of an acid protected, micro-encapsulated pancreatin preparation on pancreatogenic steatorrhea]."
03/01/1961 - "1-131 Fat-pancreatin test for steatorrhea."
06/01/1960 - "I 131-labeled fat and pancreatin as a differential absorption test in patients with steatorrhea."
|4.||Pancrelipase (Creon)FDA Link
08/01/2006 - "This randomized, placebo-controlled trial found that Creon 10 treatment controlled steatorrhea, as reflected in reduced fat excretion, decreased stool frequency and improved stool consistency. "
04/01/1988 - "An open, intraindividually controlled study with two doses of Creon (5 X 2 and 5 X 3 capsules/day) was performed in 15 patients suffering from severe pancreatic steatorrhea. "
05/01/2001 - "Are minimicrosphere pancrelipase capsules effective enough for the treatment of pancreatic steatorrhea?"
12/01/1988 - "Steatorrhea was incompletely but satisfactorily corrected by pancrelipase ECM. "
08/01/2006 - "The primary objective of this study was to compare the effect of Creon 10 with placebo in the control of steatorrhea in chronic pancreatitis patients. "
|5.||Lipase (Acid Lipase)FDA Link
09/07/2014 - "Increasing the quantity of lipase administered rarely eliminates steatorrhea but increases the cost of therapy. "
09/01/2012 - "Insufficient pancreatic enzyme dosing is common for treatment of pancreatic steatorrhea; 90 000 United States Pharmacopeia units of lipase should be given with meals. "
09/01/2010 - "Patients commonly receive insufficient lipase to abolish pancreatic steatorrhea. "
01/01/2010 - "Using such preparations, most patients will reduce their steatorrhea to <15 g fat per day during supplementation of 25,000-40,000 IU of lipase per meal, but in selected cases larger doses may be needed, depending on size of the meal and severity of the disease. "
12/01/2008 - "A low peak lipase concentration on the initial ePFT was associated with development of steatorrhea during the follow-up period (P = .02). "
10/01/1987 - "The difference in triglyceride absorption, when calculated as the area under the curve, receiving and not receiving taurine was significantly (P less than .05) correlated with the degree of steatorrhea. "
06/01/1985 - "In the 10 patients with a more severe degree of steatorrhea the decrease in fat loss approached 20% and a close relationship was found (r = 0.84, p less than 0.01) between the extent of the fatty acid loss on placebo and the decrease of this loss on taurine. "
06/01/1985 - "Twenty-two CF children with documented steatorrhea were supplemented with taurine capsules (30 mg/kg/day) and placebo during separate 6-month treatment periods. "
01/01/1990 - "We have evaluated the effect of taurine supplementation nutritional status, steatorrhea and bile acid in twenty two Cystic Fibrosis patients. "
01/01/1990 - "Steatorrhea improved significantly in six patients of group II. Glycine/taurine ratio was reduced. "
|7.||Bile Acids and Salts (Bile Acids)IBA
01/01/1975 - "Daily stool weights increased significantly in three of four patients, though none had steatorrhea; there was a significant reduction in excretion of secondary bile acids; neutral sterol degradation rates were not affected by the drug. "
11/01/1991 - "Decreased ileal reabsorption of bile salts results in fat malabsorption and steatorrhea. "
01/01/1989 - "When the concentration of conjugated bile acids in the small intestine was reduced to levels below the critical micellar concentration by several factors, fat malabsorption and subsequent steatorrhea were induced (1,-4). "
01/01/1984 - "In patients with large resection of the ileum, steatorrhea was associated with abnormality of the enterohepatic circulation of bile acids, bacterial dissemination of the small intestine and reduction of the absorption surface. "
05/01/1980 - "Patients with an interrupted enterohepatic circulation of bile acids and minimal or no steatorrhea were studied to determine if their fat absorption was aided by compensatory mechanisms which delivered increased amounts of lipid to the aqueous phase of post-prandial duodenal fluid. "
|8.||Xylose (D-Xylose)FDA Link
09/01/1996 - "The laboratory tests utilized were steatorrhea and xylose in the first years, while in recent years AGA, ARA and AEA were also utilized. "
05/01/1986 - "Although the girl was totally asymptomatic, she had steatorrhea, a delayed bone age, and an abnormal D-xylose test. "
10/01/1985 - "Steatorrhea was found in 4 of 14 patients, and D-xylose tests were abnormal in 8 of 14 patients. "
06/01/1984 - "Steatorrhea was found in 30 patients (58%) and an impaired D-xylose absorption in 52%. "
10/01/1983 - "Nineteen patients had steatorrhea, and 12 had pathological D-xylose test results. "
|9.||Dietary Fats (Ghee)IBA
08/01/2012 - "Despite treatment, 68 % of patients reported steatorrhea-related symptoms, 48 % adhered to a non-indicated dietary fat restriction, and only 33 % had visited a dietician. "
01/01/2012 - "To improve treatment efficacy, patients should be educated in adjusting the enzyme dosage according to steatorrhea-related symptoms and dietary fat intake. "
10/01/1977 - "In patients with more severe steatorrhea, decreasing dietary fat and oxalate content further reduced urinary oxalate excretion. "
11/01/1972 - " Steatorrhea was present in 4 children; deworming resulted in a reduction of fecal fat from 9.9-2.3% of dietary fat. "
03/01/2005 - "Whether this occurs in humans is unknown, but it may occur in persons with cirrhosis, who show a blunted chylomicronemic response to dietary fat without significant steatorrhea. "
|10.||alpha 1-Antitrypsin (alpha 1 Antitrypsin)IBA
01/01/1992 - "The combination of steatorrhea and normal clearance of alpha 1-antitrypsin was a modest clue for diagnosis of pancreatic malabsorption."
12/01/1983 - "A positive correlation was found between steatorrhea and stool weight but not between steatorrhea and creatorrhea or fecal clearance of alpha 1-antitrypsin. "
12/01/1983 - "The determination of steatorrhea, creatorrhea, and fecal clearance of alpha 1-antitrypsin was performed by three days stool collections. "
01/01/1992 - "We reviewed the fecal fat excretion and alpha 1-antitrypsin clearance results of 160 patients with steatorrhea in whom a final diagnosis was obtained, based on history, physical examination, and radiological, functional and morphological tests. "
01/01/1992 - "Fecal alpha 1-antitrypsin clearance in the differential diagnosis of steatorrhea."
|1.||Enzyme Replacement Therapy
04/01/1998 - "Pancreatic enzyme replacement therapy is the principal treatment method for pancreatic steatorrhea. "
07/01/1991 - "The patient remained normoglycemic after graft duodenectomy but resumed oral enzyme replacement therapy in an attempt to combat recurrence of severe steatorrhea. "
02/01/2005 - "Most cystic fibrosis (CF) patients develop steatorrhea and require pancreatic enzyme replacement therapy. "
03/01/2003 - "In some patients with severe exocrine pancreatic insufficiency, enzyme replacement therapy will not lead to clinical improvement or reduction of steatorrhea. "
10/01/2003 - "Pancreatic enzyme replacement therapy in patients with chronic pancreatitis not only reduced the extent of steatorrhea and pain, but also significantly improved a variety of other symptoms and the patient's QoL. "
06/01/2001 - "FCT, but not EL-1, values showed an inverse statistically significant correlation with steatocrit values in the whole CF group (P < 0.001); FCT was below normal in three of four CF patients with steatorrhea on pancreatic enzyme therapy. "
10/01/1982 - "Mild to moderate steatorrhea was present in all patients despite oral pancreatic enzyme therapy for 27 +/- 4 months (mean +/- SE). "
10/01/1987 - "Three control subjects and one child with cystic fibrosis and mild steatorrhea receiving enzyme therapy did not experience such an effect. "
03/01/1985 - "These data suggest that steatorrhea may be enhanced with the ingestion of high fiber diet in patients with exocrine pancreatic insufficiency on oral pancreatic enzyme therapy. "
12/01/2006 - "In 105 pancreatic insufficient CF patients (steatorrhea and low fecal elastase-1 concentrations), the effectiveness of pancreatic enzyme therapy (PET) has been assessed (fecal fat losses and coefficient of fat reabsorption). "
03/01/2004 - "Except for the patient who underwent total pancreatectomy no patient developed frank steatorrhea during long-term follow-up. "
11/01/2002 - "Central pancreatectomy affords the opportunity to save normal pancreatic tissue thus avoiding the complications of exocrine pancreatic insufficiency, namely steatorrhea and endocrine pancreatic insufficiency namely diabetes."
11/22/1953 - "[Steatorrhea and complex deficiency syndrome in subject of duodeno-pancreatectomy for cancer of Vater's ampulla]."
08/01/1985 - "When the patients who underwent pancreaticojejunostomy, pancreatectomy and other operations were compared, no significant statistical difference was noticed with regard to the incidence of immediate post-operative complications and deaths, pain relief, appearance of diabetes or steatorrhea and mortality. "
02/01/1994 - "Exocrine pancreatic function after pancreas transplantation has been maintained after orthotopic cluster transplants for malignancy, and restoration of adequate exocrine function in a previously deficient patient has been reported in a patient with chronic pancreatitis who developed labile diabetes and steatorrhea after pancreatectomy. "
|4.||Fat-Restricted Diet (Diet, Fat Restricted)
09/05/2003 - "On a low fat diet, the Slc10a2-/- mice did not have steatorrhea. "
03/01/2002 - "On a low fat diet, the Clps-/- mice did not have steatorrhea. "
11/01/1983 - "Dietary therapy includes a high-protein, high-calorie, low-fat diet often supplemented with MCTs in an effort to minimize steatorrhea. "
01/01/1989 - "A 49-year-old woman presented with chronic diarrhea and steatorrhea due to bile acid malabsorption which was strikingly improved by a low-fat diet. "
01/01/2013 - "Liver steatosis can be avoided by the use of intestine-specific MTP inhibitors, while steatorrhea by low-fat diet. "
11/01/1951 - "Correction of steatorrhea in bile fistula dogs by duodenal and oral administration of bile substitutes."
02/29/1964 - "The benefit resulting from the oral administration of broad-spectrum antibiotics to a group of patients with secondary steatorrhea supports this concept."
08/01/1992 - "The results indicate that oral administration of cholylsarcosine improved dietary fat absorption in a canine model of severe bile acid malabsorption with associated steatorrhea and bile acid deficiency in the proximal small intestine. "
11/09/1963 - "The intestinal absorption of folic acid in patients with idiopathic steatorrhea was studied by the oral administration of tritium-labelled folic acid in a dosage of 15 mug./kg. Results were expressed as a percentage of the orally administered folic acid radioactivity excreted in the urine over 24 hours. "
08/01/1989 - "Pancreatic duct ligation resulted in a significant (P less than 0.001) decrease in cobalamin absorption, which was not restored by oral administration of bovine pancreatic enzymes, despite considerable improvements in steatorrhea and in vivo proteolytic activities. "