Natriuretic Peptides

Peptides that regulate the WATER-ELECTROLYTE BALANCE in the body, also known as natriuretic peptide hormones. Several have been sequenced (ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; C-TYPE NATRIURETIC PEPTIDE).

Also Known As:

Networked: 3754 relevant articles (121 outcomes, 498 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Januzzi, James L: 71 articles (01/2022 - 06/2004)
2.	Burnett, John C: 47 articles (01/2022 - 02/2002)
3.	Richards, A Mark: 42 articles (10/2021 - 01/2002)
4.	Mueller, Christian: 36 articles (01/2022 - 07/2007)
5.	Solomon, Scott D: 36 articles (01/2022 - 10/2013)
6.	Wang, Thomas J: 36 articles (01/2022 - 08/2002)
7.	Maisel, Alan: 30 articles (11/2021 - 01/2002)
8.	Maisel, Alan S: 30 articles (10/2021 - 06/2004)
9.	de Boer, Rudolf A: 28 articles (02/2022 - 08/2008)
10.	Anker, Stefan D: 27 articles (01/2022 - 09/2008)

Related Diseases

1.	Heart Failure 01/01/1996 - "Providing open access echocardiography, and/or targeting this resource to the most deserving cases by measuring plasma natriuretic peptides may help to optimize the use of this technique while improving the diagnosis of heart failure patients. " 07/03/2013 - "To determine the efficacy of a screening program using brain-type natriuretic peptide (BNP) and collaborative care in an at-risk population in reducing newly diagnosed heart failure and prevalence of significant left ventricular (LV) systolic and/or diastolic dysfunction. " 01/01/2021 - "Natriuretic peptides are helpful in detecting chronic heart failure (HF) in primary care; however, there are a lack of data evaluating thresholds recommended by clinical guidelines. " 01/01/2020 - "Is natriuretic peptide lowering strategy superior to symptomatically based management of chronic heart failure with reduced ejection fraction?" 09/01/2012 - "In humans with congestive heart failure (CHF), better outcome is correlated with lower natriuretic peptide (NP) levels after starting treatment and greater percentage reduction of NP levels. "
2.	Myocardial Infarction 01/01/2014 - "Natriuretic peptides as an adjunctive treatment for acute myocardial infarction: insights from the meta-analysis of 1,389 patients from 20 trials." 04/01/2013 - "The aim of this study was to compare the prognostic value of matrix metalloproteinase-3 and -9, and NT-pro-natriuretic peptide for fatal and nonfatal complications in Q-wave myocardial infarction patients in the acute and postinfarction periods. " 04/12/2007 - "The objective of this study was to assess natriuretic peptide release following acute myocardial infarction, and its relationship with ventricular function. " 09/01/2005 - "Few studies have compared the relative prognostic value of different natriuretic peptides after acute myocardial infarction (AMI). " 01/01/2023 - "In patients with acute myocardial infarction (AMI), elevated natriuretic peptide (NP) concentrations are reportedly associated with worse clinical outcomes. "
3.	Fibrosis (Cirrhosis) 01/01/2023 - "However, the effects of natriuretic peptide receptor C (NPRC) on cardiac fibrosis in DCM remains unknown. " 09/21/2015 - "Contrary to natriuretic peptides, gal-3 is hemodynamically stable which is an additional asset of gal-3 as a marker of myocardial fibrosis.The" 09/01/2015 - "Hypertrophic marker genes, extracellular matrix-regulating factors, and expression patterns of fibrosis markers were examined in αMHC-AT1R(tg/+) ventricles (with or without SIL) and corroborated by investigating different components of the natriuretic peptide/PDE5/cGMP pathway as well as cardiac functions. " 07/01/2012 - "Natriuretic peptides produced by the heart in response to cardiac overload exert cardioprotective and renoprotective effects by eliciting natriuresis, reducing BP, and inhibiting cell proliferation and fibrosis. " 04/01/2006 - "Constitutive and sympathetic-driven natriuretic peptide synthesis by myofibroblasts may in part influence reparative fibrosis."
4.	Heart Diseases (Heart Disease) 03/14/2008 - "Natriuretic peptides (NPs) show promise in screening asymptomatic populations for structural heart disease, but little is known about their use in student athletes. " 09/30/2011 - "Numerous clinical studies have addressed the role of the natriuretic peptide system either as a diagnostic tool or as a guide to treatment in many cardiac diseases. " 01/01/2010 - "An astonishing amount of clinical studies have established cardiac natriuretic peptides and their molecular precursors as useful markers of heart disease. " 01/01/2008 - "Several studies have demonstrated that higher circulating levels of natriuretic peptides represent a strong independent risk factor for major cardiovascular complications and/or death, even in extra-cardiac diseases. " 11/01/2004 - "2. Recent studies have identified additional modes of action of the natriuretic peptides that may also confer cardioprotective benefits, especially in heart disease. "
5.	Cardiovascular Diseases (Cardiovascular Disease) 12/01/2023 - "This study assessed the prognostic value of combined B-type natriuretic peptides (BNP) measurement and quantitative myocardial perfusion scan (MPS) data for cardiac events (CE). " 01/27/2023 - "Our study reveals ANGII as a natural suppressor for cGMP-generating action of GC-A via AT1/PKC dependent manner and highlights importance of dual-targeting RAAS and NPS in maximizing beneficial properties of natriuretic peptides in cardiovascular disease." 01/01/2023 - "Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk: a Mendelian randomization study." 06/27/2022 - "In perspective, studies on natriuretic peptides in the heart have shown that the post-translational phase of gene expression is not only relevant for human physiology but may prove implicated also in the development and, perhaps one day, cure of human cardiovascular disease." 01/01/2018 - "Recent studies have suggested that the natriuretic peptide system may be endogenously suppressed in black individuals who are free of prevalent cardiovascular disease. "

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	Brain Natriuretic Peptide (Natrecor)
3.	pro-brain natriuretic peptide (1-76)
4.	Atrial Natriuretic Factor (ANF)
5.	Troponin
6.	Natriuretic Peptides
7.	Neprilysin (Neutral Endopeptidase)
8.	Diuretics
9.	Nitric Oxide (Nitrogen Monoxide)
10.	Angiotensin II

Related Therapies and Procedures

1.	Therapeutics
2.	Heart Transplantation (Grafting, Heart)
3.	Vagus Nerve Stimulation
4.	Transplantation
5.	Renal Dialysis (Hemodialysis)