Cytochromes a

A subclass of heme a containing cytochromes that have two imidazole nitrogens as axial ligands and an alpha-band absorption of 605 nm. They are found in a variety of microorganisms and in eucaryotes as a low-spin cytochrome component of MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.

Also Known As:

Cytochrome a

Networked: 13 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Cytochromes: 2196
  - Cytochrome a Group
    - Cytochromes a: 13
      - cytochrome caa(3)
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Hemeproteins: 194
    - Cytochromes: 2196
      - Cytochrome a Group
        Cytochromes a: 13
        cytochrome caa(3)

Experts

1.	Marchenko, M M: 2 articles (11/2012 - 09/2012)
2.	Voloshchuk, O N: 2 articles (11/2012 - 09/2012)
3.	Mudrak, M S: 1 article (11/2012)
4.	Boveris, Alberto: 1 article (06/2009)
5.	Bández, Manuel J: 1 article (06/2009)
6.	Ferrer, Isidro: 1 article (06/2009)
7.	Gómez, Carmen: 1 article (06/2009)
8.	Muntané, Gerard: 1 article (06/2009)
9.	Navarro, Ana: 1 article (06/2009)
10.	Sánchez-Pino, María Jesús: 1 article (06/2009)

Related Diseases

1.	Fibrosis (Cirrhosis) 03/01/1985 - "Using repeated operative biopsies the author examined changes in the concentration of cytochromes a, b, c1 and c in mitochondrial protein of hepatocytes during the development of cirrhosis in rabbit liver. " 01/01/2022 - "However, in the context of compensated cirrhosis and concomitant administration of inhibitors of cytochromes, a careful monitoring of liver biomarkers, as well as therapeutic drug monitoring (TDM), may be advisable during GLE/PIB therapy. "
2.	Carcinoma (Carcinomatosis) 11/01/2012 - "The maximal reduction in the mitochondrial cytochromes a, b and c content was observed at the terminal stage of Guerin's carcinoma. " 09/01/2012 - "The preliminary low-level irradiation leading to the mitochondrial cytochrome a, b and c content reduction at the latent stage of Guerin's carcinoma is shown. "
3.	Photophobia (Light Sensitivity) 07/21/2000 - "Exploiting the unique light sensitivity of the cytochrome a(2+)(3)-NO, we show that under turnover conditions, depending on the cytochrome c(2+) concentration, either the cytochrome a(2+)(3)-NO or the nitrite-bound enzyme is formed. "
4.	Liver Failure 05/01/1974 - "Clinical application of cytochrome A assay of liver specimens for operative indication in critically ill patients with liver failure."
5.	Critical Illness (Critically Ill) 05/01/1974 - "Clinical application of cytochrome A assay of liver specimens for operative indication in critically ill patients with liver failure."

Related Drugs and Biologics

1.	Cytochromes c (Cytochrome c)
2.	Cytochromes c2
3.	Mitochondrial Proteins (Mitochondrial Protein)
4.	Nitric Oxide Synthase (NO Synthase)
5.	Thiobarbituric Acid Reactive Substances
6.	Biomarkers (Surrogate Marker)
7.	Superoxide Dismutase
8.	Proteins (Proteins, Gene)
9.	Oxyhemoglobins (Oxyhemoglobin)
10.	Oxygen (Dioxygen)

Related Therapies and Procedures

1.	Therapeutics