Progesterone Congeners

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136 relevant articles (3 outcomes, 15 trials/studies) found for this Bio-Agent

Description: Steroidal compounds related to PROGESTERONE, the major mammalian progestational hormone. Progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.

Also Known As:

Progestagens, Synthetic; Progestational Hormone Analogs; Progestational Hormone Analogues; Progestational Hormones, Synthetic; Progestin Analogs; Progestin Analogues; Progestins, Synthetic; Progestogens, Synthetic; Synthetic Progestational Hormones; Synthetic Progestins; Synthetic Progestagens; Synthetic Progestogens

Relationship Network

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists

Hormones: 46253

Gonadal Hormones: 260

Gonadal Steroid Hormones: 2275

Progesterone Congeners: 136

Progesterone: 7203

Pregnenolone: 212

chlorpromadinone acetate: 1

Duogestral

Experts

1.	Tilley, Wayne D: 1 article (08/2007)
2.	Birrell, Stephen N: 1 article (08/2007)
3.	Butler, Lisa M: 1 article (08/2007)
4.	Harris, Jonathan M: 1 article (08/2007)
5.	Buchanan, Grant: 1 article (08/2007)
6.	Hyder, Salman M: 1 article (07/2006)
7.	Schnell, Jennifer: 1 article (07/2006)
8.	Ellersieck, Mark R: 1 article (07/2006)
9.	Molinolo, Alfredo: 1 article (07/2006)
10.	Brandt, Sandra: 1 article (07/2006)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 01/01/1995 - "High doses of oral synthetic progestins are effective in the treatment of breast cancer.(ABSTRACT TRUNCATED AT 250 WORDS)" 10/15/2007 - "Recent clinical trials indicate that synthetic progestins may stimulate progression of breast cancer in postmenopausal women, a result that is consistent with studies in chemically-induced breast cancer models in rodents. " 10/01/1991 - "This study documents a biphasic change in the rate of cell cycle progression and proliferation of T-47D human breast cancer cells treated with synthetic progestins, consisting of an initial transient acceleration in transit through G1, followed by cell cycle arrest and growth inhibition. " 07/01/1980 - "A study was made of basic mechanisms involved in regression of breast cancer exposed to high levels of synthetic progestins. " 09/01/2009 - "Regulation of thrombospondin-1 by natural and synthetic progestins in human breast cancer cells." Order ALL the reference details at left...
2.	Hyperplasia 12/01/1997 - "The good results with natural and synthetic progestins suggest that this treatment can be used both in premenopause and postmenopause hyperplasia. " 01/01/2000 - "These studies shed new light on the mechanism of progesterone-induced mammary hyperplasia and urges for further research on potential adverse effects of synthetic progestins." 03/01/2004 - "According to clinical manifestations of hyperplasia, the patients were divided into 3 groups: 74 (53%) had reestablishing menstrual function after total curettage (group 1); 42 patients (30%) with glandular-cystic hyperplasia after curettage and hormonal therapy with progesterone and synthetic progestins (duration 3 to 6 months) had no repeated pathology of the endometrium (group 2); endometrial hyperplasia recurred 2 and 3 times as showed biopsies during 2-5 years of observation in 23 (17%) women (group 3). " 01/01/2000 - "Toxicity studies using beagle dogs revealed in the 1980s that synthetic progestins may induce a syndrome of growth hormone (GH) excess, known as acromegaly, and the development of predominantly benign mammary hyperplasia. " Order ALL the reference details at left...
3.	Neoplasms (Cancer) 02/15/2002 - "This first, large scale study of PR gene regulation has important implications for the measurement of PR in breast cancers and for the many clinical uses of synthetic progestins. " 01/01/1976 - "[Synthetic progestins in combined treatment of cancer of the uterine body]" 07/01/1988 - "Stimulatory effect of synthetic progestins currently used for the treatment of prostate cancer on growth of the androgen-sensitive Shionogi tumor in mice." 07/01/2006 - "Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats." 01/01/1992 - "Tumor stimulatory effects of progesterone or synthetic progestins can be observed under some conditions in rodents as well as in cats and monkeys. " Order ALL the reference details at left...
4.	Syndrome 01/01/2000 - "Toxicity studies using beagle dogs revealed in the 1980s that synthetic progestins may induce a syndrome of growth hormone (GH) excess, known as acromegaly, and the development of predominantly benign mammary hyperplasia. " 07/01/1978 - "We have found a specific binding protein for synthetic progestins 6,7-[3H]methyltrienolone (R1881) and 17,21-dimethyl-19-norpregna-4,9-diene-3,20-dione (R5020) and in the testis cytosol from three "sisters" with the complete form of the testicular feminization syndrome. " Order ALL the reference details at left...
5.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 09/01/1971 - "[Treatment of prostatic hypertrophy with synthetic progestational hormones]" 01/01/1973 - "[Studies using synthetic progestogens in drug therapy of so-called prostatic hypertrophy]" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Tamoxifen
2.	Progesterone
3.	Estrogens (Estrogen)
4.	Hormones
5.	Growth Hormone (Somatotropin)
6.	Oral Contraceptives
7.	Steroid Receptors (Steroid Receptor)
8.	Lipids
9.	Insulin-Like Growth Factor I (IGF-1)
10.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)

Related Therapies and Procedures

1.	Hormone Replacement Therapy (Therapy, Hormone Replacement)
2.	Drug Therapy (Chemotherapy)
3.	Estrogen Replacement Therapy
4.	Injections
5.	Curettage

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