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Methenyltetrahydrofolate Cyclohydrolase

An aminohydrolase that catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate. In most higher eucaryotic organisms this enzyme also includes METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP) and FORMATE-TETRAHYDROFOLATE LIGASE activities.
Also Known As:
5,10-MTHF Cyclohydrolase; 5,10-Methenyltetrahydrofolate 5-Hydrolase (Decyclizing); 5,10-Methenyltetrahydrofolate Cyclohydrolase; 5,10 MTHF Cyclohydrolase; 5,10 Methenyltetrahydrofolate Cyclohydrolase; Cyclohydrolase, 5,10-MTHF; Cyclohydrolase, 5,10-Methenyltetrahydrofolate; Cyclohydrolase, Methenyltetrahydrofolate
Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lianeri, Margarita: 2 articles (01/2010 - 06/2007)
2. Scott, John M: 2 articles (04/2009 - 11/2002)
3. Parle-McDermott, Anne: 2 articles (04/2009 - 11/2002)
4. Kirke, Peadar N: 2 articles (04/2009 - 11/2002)
5. Brody, Lawrence C: 2 articles (04/2009 - 11/2002)
6. Molloy, Anne M: 2 articles (04/2009 - 11/2002)
7. Mills, James L: 2 articles (04/2009 - 11/2002)
8. Watkins, David: 1 article (07/2012)
9. Rosenblatt, David S: 1 article (07/2012)
10. Jagodziński, Paweł P: 1 article (01/2010)

Related Diseases

1. Neural Tube Defects (Exencephaly)
2. Schizophrenia (Dementia Praecox)
3. Neoplasms (Cancer)
4. Migraine Disorders (Migraine)
5. Laryngeal Neoplasms (Laryngeal Cancer)

Related Drugs and Biologics

1. Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)
2. Formate-Tetrahydrofolate Ligase
3. 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase (Methyltetrahydrofolate Homocysteine Methyltransferase)
4. Oxidoreductases
5. Ligases
6. Folic Acid (Vitamin M)
7. 5,10-methylenetetrahydrofolate
8. 10-formyltetrahydropteroylglutamic acid
9. Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)
10. Thymidylate Synthase