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3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.
Also Known As:
3 alpha-Hydroxysteroid Dehydrogenase; 3 alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3 alpha-Hydroxysteroid Oxidoreductase; 3alpha-Hydroxysteroid Dehydrogenase (B-specific); 5 alpha-3 alpha-Hydroxysteroid Dehydrogenase; 5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase; 5-DP-3 alpha-HSO; NADPH-5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase; 3 alpha Hydroxysteroid Dehydrogenase; 3 alpha Hydroxysteroid Oxidoreductase; 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase; Dehydrogenase, 3 alpha-Hydroxysteroid; NADPH 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase; Oxidoreductase, 3 alpha-Hydroxysteroid
Networked: 15 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Luisi, Stefano: 1 article (04/2003)
2. Casarosa, Elena: 1 article (04/2003)
3. Ludwig, Michael: 1 article (04/2003)
4. Elger, Christian E: 1 article (04/2003)
5. Stoffel-Wagner, Birgit: 1 article (04/2003)
6. Clusmann, Hans: 1 article (04/2003)
7. Watzka, Matthias: 1 article (04/2003)
8. Beyenburg, Stefan: 1 article (04/2003)
9. Steckelbroeck, Stephan: 1 article (04/2003)
10. Bidlingmaier, Frank: 1 article (04/2003)

Related Diseases

1. Open-Angle Glaucoma (Glaucoma, Open Angle)
2. Neoplasms (Cancer)
3. Feminization
4. Carcinoma (Carcinomatosis)
5. Adenoma (Adenomas)

Related Drugs and Biologics

1. Cholestenone 5 alpha-Reductase (5 alpha-Reductase)
2. Oxidoreductases
3. Testosterone (Sustanon)
4. Lithocholic Acid
5. Estradiol (Estrace)
6. Deoxycholic Acid (Sodium Deoxycholate)
7. Chenodeoxycholic Acid (Chenix)
8. Bile Acids and Salts (Bile Acids)
9. 20-alpha-Hydroxysteroid Dehydrogenase
10. Protein Isoforms (Isoforms)