|1.||Lagiou, Pagona: 6 articles (01/2010 - 01/2004)|
|2.||Negri, Eva: 5 articles (01/2010 - 04/2005)|
|3.||La Vecchia, Carlo: 5 articles (01/2010 - 04/2005)|
|4.||Bosetti, Cristina: 4 articles (01/2010 - 04/2005)|
|5.||Franceschi, Silvia: 4 articles (08/2008 - 04/2005)|
|6.||Chu, Shu-Chen: 3 articles (01/2014 - 01/2007)|
|7.||Hsieh, Yih-Shou: 3 articles (01/2014 - 01/2007)|
|8.||Li, Feng: 3 articles (10/2010 - 07/2009)|
|9.||Kadota, Shigetoshi: 3 articles (10/2010 - 07/2009)|
|10.||Tezuka, Yasuhiro: 3 articles (10/2010 - 07/2009)|
|1.||Cardiovascular Diseases (Cardiovascular Disease)
09/12/2012 - "Therefore, further research is needed to better evaluate and understand the protective effects of flavanones in cardiovascular diseases."
09/12/2012 - "Although flavanones may be promising compounds that are particularly active in cardiovascular disease prevention, clinical data are still scarce and most in vitro data have been obtained under nonphysiologically relevant conditions. "
11/01/2006 - "Flavanones, the main polyphenols of citrus fruits, are thought to contribute to the protective effects of these fruits against cardiovascular diseases and cancer. "
02/13/2008 - "Diets rich in citrus and citrus-based products have been negatively correlated with the risk of cardiovascular disease, but so far no studies have been conducted to determine whether naringenin and hesperetin, two major flavanones in citrus plants, influence endothelium nitric oxide (NO) production. "
09/01/2015 - "Recent studies have pointed to a reduction in the incidence of some cancers, diabetes, and neuro-degenerative diseases as a result of human health benefits from flavanones. "
01/01/2012 - "The aim of this study was to examine the cytotoxic and apoptotic activities of TRAIL on HeLa cancer cells in combination with two synthetic compounds: 6-hydroxyflavanone (6-HF) and its derivative 6-propionoxy-flavanone (6-PF) and to determine the mechanism by which the flavanones overcome the TRAIL-resistance. "
12/01/2012 - "A series of halogenated flavanones were synthesized from 2-hydroxychalcones and tested for their cytotoxicity against a panel of human cancer cell lines. "
05/01/2012 - "Natural flavanones exhibit cancer preventive and/or therapeutic effects. "
03/01/2012 - "Flavanones inhibit the clonogenicity of HCT116 cololectal cancer cells."
|3.||Hepatocellular Carcinoma (Hepatoma)
09/01/2015 - "In conclusion, the prenylated flavanones addisoniaflavanones I and II may be of interest for pharmacological purposes due to their high cytotoxic and pro-apoptotic potential against hepatoma cells."
09/01/2015 - "addisoniae, three (1, 2, 4) and three known (3, 5, 6) flavanones were isolated: addisoniaflavanones I and II, containing either a 2″,3″-epoxyprenyl moiety (1) or a 2″,3″-dihydroxyprenyl moiety (2) were shown to be highly toxic (MTT assay: EC50 values of 5.25±0.7 and 8.5±1.3 μM, respectively) to H4IIE hepatoma cells. "
01/01/2012 - "In this study, 12 novel prenylated flavanones were synthesised in our laboratory and their activities were assessed for two human prostate cancer cell lines, PC-3 and DU-145, and a human hepatoma cell line, Hep-3B. "
06/01/2003 - "Activity-guided fractionation of an EtOAc-soluble extract of the leaves of Muntingia calabura collected in Peru, using an in vitro quinone reductase induction assay with cultured Hepa 1c1c7 (mouse hepatoma) cells, resulted in the isolation of a flavanone with an unsubstituted B-ring, (2R,3R)-7-methoxy-3,5,8-trihydroxyflavanone (5), as well as 24 known compounds, which were mainly flavanones and flavones. "
04/01/2015 - "We investigated whether flavanones, hesperetin-naringenin, orange, and grapefruit juices reduce airway inflammation and remodeling in murine chronic asthma model. "
04/01/2009 - "Flavonoids are divided into flavones, flavonols, flavanones, and isoflavones etc. according to their basal structure, and are known to include compounds with physiological and pharmacological effects such as anti-oxidant, anti-tumor, and anti-inflammation activities. "
10/01/2005 - "We examined the inhibitory activities of various flavonoids, including the flavanones, flavones/isoflavones and flavonols, on collagenase from Clostridium histolyticum to establish their therapeutic potential against skin inflammation and photoaging. "
02/01/2013 - "Different classes of flavonoids (chalcones, flavones, isoflavones, flavanols, flavanones and anthocyanins) are synthetically mimicked using natural product structure-antioxidant activity relationships that are relevant for their enhanced function against cancer as well as severe inflammation conditions under which an increased oxidative stress is often implicated. "
12/01/2003 - "The anti-inflammatory activities of flavonols (quercetin, rutin and morin) and flavanones (hesperetin and hesperidin) were investigated in animal models of acute and chronic inflammation. "
|5.||Breast Ductal Carcinoma