|1.||Njoroge, Sarah W: 2 articles (01/2015 - 02/2012)|
|2.||Laposata, Michael: 2 articles (01/2015 - 02/2012)|
|3.||Seegmiller, Adam C: 2 articles (01/2015 - 02/2012)|
|4.||Cui, Hengmi: 1 article (09/2015)|
|5.||Xia, Lili: 1 article (09/2015)|
|6.||Gong, Daoqing: 1 article (09/2015)|
|7.||Montgomery, Sean: 1 article (09/2015)|
|8.||Li, Fuyuan: 1 article (09/2015)|
|9.||Zhang, Yihui: 1 article (09/2015)|
|10.||Wang, Qianqian: 1 article (09/2015)|
01/01/2015 - "Higher expression of TCF7L2 and the fatty acid desaturases FADS1, FADS2 and SCD could contribute to insulin resistance. "
02/01/2008 - "Fatty acid desaturases in human adipose tissue: relationships between gene expression, desaturation indexes and insulin resistance."
07/01/2011 - "Increasing evidence suggests that fatty acid desaturases, rate-limiting enzymes in unsaturated fatty acid biosynthesis, are important factors in the pathogenesis of lipid-induced insulin resistance. "
03/01/1988 - "Although desaturase activities in experimental tumors have been evaluated, to our knowledge, fatty acid desaturases in human neoplasms and particularly in human tumors grown in nude mice have not been assessed yet. "
01/01/2011 - "Genes coding for the fatty acid desaturases (FADS1, 2, 3) localized at the cancer genomic hotspot 11q13 locus are required for the biosynthesis of 20 carbon polyunsaturated fatty acids (PUFA) that are direct eicosanoid precursors. "
|3.||Cystic Fibrosis (Mucoviscidosis)
01/01/2015 - "Polyunsaturated fatty acid supplementation reverses cystic fibrosis-related fatty acid abnormalities in CFTR-/- mice by suppressing fatty acid desaturases."
02/01/2012 - "Patients and models of cystic fibrosis (CF) exhibit consistent abnormalities of polyunsaturated fatty acid composition, including decreased linoleate (LA) and docosahexaenoate (DHA) and variably increased arachidonate (AA), related in part to increased expression and activity of fatty acid desaturases. "
|4.||Atherosclerotic Plaque (Atheroma)
06/01/2015 - "Increased fatty acid desaturases 1 and 2 and acyl-CoA synthase long-chain family member 3 mRNA levels as well as increased arachidonic acid to linoleic acid and docosahexaenoic acid to eicosapentaenoic acid ratios were also found in atheroma plaque and peritoneal foam cells from LXR agonist-treated mice. "
|1.||Linoleic Acid (Linoleate)
|2.||Arachidonic Acid (Vitamin F)
|9.||Messenger RNA (mRNA)