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beta-Transducin Repeat-Containing Proteins

A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
Also Known As:
beta-TrCP; beta-Transducin Repeat-Containing Protein; betaTrCP; Protein, beta-Transducin Repeat-Containing; Repeat-Containing Protein, beta-Transducin; Repeat-Containing Proteins, beta-Transducin; beta TrCP; beta Transducin Repeat Containing Protein; beta Transducin Repeat Containing Proteins
Networked: 49 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Fuchs, Serge Y: 7 articles (04/2009 - 03/2004)
2. Wang, Yi-Ching: 3 articles (02/2010 - 09/2009)
3. Hsu, Han-Shui: 3 articles (02/2010 - 09/2009)
4. Wei, Shuo: 3 articles (07/2009 - 09/2007)
5. Chen, Ching-Shih: 3 articles (07/2009 - 09/2007)
6. Li, Ying: 3 articles (03/2008 - 03/2005)
7. Benarous, Richard: 3 articles (02/2007 - 01/2006)
8. Pietsch, Torsten: 3 articles (06/2005 - 08/2002)
9. Tzao, Ching: 2 articles (01/2010 - 09/2009)
10. Chuang, Hsiao-Ching: 2 articles (07/2009 - 09/2008)

Related Diseases

1. Neoplasms (Cancer)
2. Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
3. Lung Neoplasms (Lung Cancer)
4. Squamous Cell Carcinoma (Epidermoid Carcinoma)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. beta-Transducin Repeat-Containing Proteins
2. beta Catenin
3. Proteins (Proteins, Gene)
4. Glycogen Synthase Kinases
5. glycogen synthase kinase 3 beta
6. Lysine (L-Lysine)
7. Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
8. Ubiquitin
9. Proteasome Endopeptidase Complex (Proteasome)
10. Cyclin D1