|1.||Fan, Jun-Bao: 1 article (11/2015)|
|2.||Arimoto, Kei-Ichiro: 1 article (11/2015)|
|3.||Liu, Chang-Wei: 1 article (11/2015)|
|4.||Liu, Dan: 1 article (11/2015)|
|5.||Miyauchi-Ishida, Sayuri: 1 article (11/2015)|
|6.||Yan, Ming: 1 article (11/2015)|
|7.||Győrffy, Balázs: 1 article (11/2015)|
|8.||Zhang, Dong-Er: 1 article (11/2015)|
|9.||Ishii, Megumi: 1 article (01/2015)|
|10.||Maeda, Ayumi: 1 article (01/2015)|
10/01/2012 - "Nevertheless, only three substrates have been identified so far to which FAT10 becomes covalently attached through a non-reducible isopeptide bond, and these are the FAT10-conjugating enzyme USE1 which auto-FAT10ylates itself in cis, the tumor suppressor p53 and the ubiquitin-activating enzyme UBE1 (UBA1). "
08/15/2011 - "Ubiquitin-activating enzyme 1 (UBE1) is a critical regulator of the ubiquitination cycle and its targeted inhibition may be an appropriate therapeutic strategy as tumor cells are reported to have increased dependence on protein ubiquitination. "
08/15/2011 - "Protein cross-linking as a novel mechanism of action of a ubiquitin-activating enzyme inhibitor with anti-tumor activity."
10/01/2007 - "Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics."
01/01/2008 - "Inhibiting Hdm2 and ubiquitin-activating enzyme: targeting the ubiquitin conjugating system in cancer."
|2.||Parkinson Disease (Parkinson's Disease)
09/01/2010 - "The aim of the present study is to explore whether ubiquitin-activating enzyme E1, ubiquitin-conjugating enzyme E2, ubiquitin or proteasome activity are affected in peripheral blood mononuclear cells (PBMC) of AD, mild cognitive impairment (MCI) and Parkinson's disease (PD) patients compared to healthy subjects. "
01/01/1987 - "Cells of the FM3A ts85 mutant, which have a thermolabile ubiquitin activating enzyme (E1), do not accelerate protein degradation in response to a 43 degrees C heat shock, whereas wild-type FM3A mouse cells do. "
03/15/2014 - "Cloning of ubiquitin-activating enzyme and ubiquitin-conjugating enzyme genes from Gracilaria lemaneiformis and their activity under heat shock."
09/01/1991 - "There is no change in synthesis of the constitutive form of SP 70 or of the ubiquitin activating enzyme E1 during heat shock or glucose starvation. "
|5.||Lung Neoplasms (Lung Cancer)
03/15/2000 - "The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines."
07/01/1993 - "A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme."
01/01/1995 - "The human UBE1L gene, for which the product may well play a role in the ubiquitin system because of its high degree of identity to the ubiquitin activating enzyme, is located at 3p21, a chromosomal region consistently showing loss of heterozygosity in lung cancer. "
|2.||Proteasome Endopeptidase Complex (Proteasome)
|3.||Adenosine Triphosphatases (ATPase)
|5.||Proteins (Proteins, Gene)
|8.||Complementary DNA (cDNA)