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PAR-1 Receptor

A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.
Also Known As:
Receptor, PAR-1; PAR1 Receptor; Proteinase-Activated Receptor 1; PAR 1 Receptor; Protease Activated Receptor 1; Proteinase Activated Receptor 1; Receptor, PAR 1; Receptor, PAR1; Protease-Activated Receptor 1
Networked: 152 relevant articles (4 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Bar-Shavit, Rachel: 6 articles (05/2012 - 01/2005)
2. Ruf, Wolfram: 5 articles (04/2012 - 07/2004)
3. Covic, Lidija: 5 articles (06/2011 - 03/2006)
4. Kuliopulos, Athan: 5 articles (06/2011 - 03/2006)
5. Aylward, Philip E: 4 articles (11/2015 - 08/2014)
6. Hollenberg, Morley D: 4 articles (11/2015 - 03/2003)
7. Van de Werf, Frans: 4 articles (01/2015 - 10/2012)
8. Griffin, John H: 4 articles (04/2013 - 11/2006)
9. Salah, Zaidoun: 4 articles (05/2012 - 01/2005)
10. Maoz, Myriam: 4 articles (01/2010 - 01/2005)

Related Diseases

1. Acute Coronary Syndrome
2. Coronary Artery Disease (Coronary Atherosclerosis)
3. Stroke (Strokes)
4. Sepsis (Septicemia)
5. Myocardial Infarction

Related Drugs and Biologics

1. Protein C
2. PAR-2 Receptor
3. Thrombin
4. Thrombin Receptors (Thrombin Receptor)
5. 2-f)quinazoline-1,3-diamine N3- cyclopropyl- 7- ((4- (1- methylethyl)phenyl)methyl)- 7H- pyrrolo(3
6. Prothrombin (Factor II)
7. thrombin receptor peptide SFLLRNP
8. Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)
9. Calcium
10. factor V Leiden

Related Therapies and Procedures

1. Lasers (Laser)
2. Quantum Dots (Quantum Dot)
3. Transplants (Transplant)
4. Thrombolytic Therapy
5. Homologous Transplantation (Allograft)