5-HT2B Serotonin Receptor

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20 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs. A number of functions have been attributed to the action of the 5-HT2B receptor including the development of cardiac myocytes (MYOCYTES, CARDIAC) and the contraction of SMOOTH MUSCLE.

Also Known As:

Receptor, Serotonin, 5-HT2B; (5-HT)2B Receptors; 5-HT2B Receptor; 5-Hydroxytryptamine 2B Receptor; Receptor, Serotonin 2B; Serotonin 2B Receptors; 2B Receptor, 5-Hydroxytryptamine; 2B Receptor, Serotonin; 2B Receptors, Serotonin; 5 HT2B Receptor; 5 Hydroxytryptamine 2B Receptor; Receptor, 5-HT2B; Receptor, 5-Hydroxytryptamine 2B; Receptors, Serotonin 2B; Serotonin 2B Receptor

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 56522

Membrane Proteins: 4214

Cell Surface Receptors: 633

G-Protein-Coupled Receptors: 403

Serotonin Receptors: 406

5-HT2 Serotonin Receptors: 28

5-HT2B Serotonin Receptor: 20

Neurotransmitter Receptors: 266

Biogenic Amine Receptors: 3

Serotonin Receptors: 406

5-HT2 Serotonin Receptors: 28

5-HT2B Serotonin Receptor: 20

Biogenic Amine Receptors: 3

Serotonin Receptors: 406

5-HT2 Serotonin Receptors: 28

5-HT2B Serotonin Receptor: 20

Experts

1.	Maroteaux, Luc: 4 articles (08/2008 - 07/2003)
2.	Jaffré, Fabrice: 3 articles (08/2008 - 07/2003)
3.	Monassier, Laurent: 3 articles (08/2008 - 07/2003)
4.	Nebigil, Canan G: 3 articles (08/2004 - 07/2003)
5.	Launay, Jean-Marie: 2 articles (08/2004 - 07/2003)
6.	Laplante, Marc-André: 1 article (08/2008)
7.	Bousquet, Pascal: 1 article (08/2008)
8.	de Champlain, Jacques: 1 article (08/2008)
9.	Frisina, Robert D: 1 article (07/2007)
10.	Zhu, XiaoXia: 1 article (07/2007)

Related Diseases

1.	Hypertension (High Blood Pressure) 01/01/2004 - "The 5-HT2B receptor is also implicated in systemic hypertension" 07/01/2001 - "Also, the involvement of the 5-HT2B receptor in the vascular growth often observed in hypertension is likely" 03/01/1999 - "We hypothesized that the 5-HT2B receptor may play a role in maintaining the high blood pressure of DOCA-salt-hypertensive rats, and herein we provide data connecting in vitro and in vivo findings" 05/01/2007 - "With the knowledge that (+)-norfenfluramine also has affinity for 5-HT2B receptors and that arterial 5-HT2B receptor expression is up-regulated in deoxycorticosterone acetate (DOCA)-salt hypertension, we tested the hypothesis that (+)-norfenfluramine-induced vasoconstriction and pressor effects are potentiated in DOCA-salt hypertensive rats in a 5-HT2 receptor-dependent manner" Get all the results and reference details, order at left...
2.	Pulmonary Hypertension (Ayerza Syndrome) 01/01/2007 - "A heterozygous mutation was identified in the 5-HT2B receptor gene of a patient who developed pulmonary hypertension after fenfluramines anorexigen treatment" 01/01/2004 - "Furthermore, mice with pharmacological or genetic ablation of 5-HT2B receptor are totally resistant to hypoxia-induced pulmonary hypertension, indicating that this receptor is regulating the pathologic vascular proliferation leading to this disease" 10/01/2002 - "Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension." Get all the results and reference details, order at left...
3.	Seizures (Seizure) 10/16/1998 - "In contrast, the 5-HT2B receptor agonist 1-[5-(2-thienylmethoxy)-1H-3-indoyl]propan-2-amine hydrochloride (BW-723C86; 3-30 mg/kg s.c.) had no effect on the threshold for generalised seizures in any of the models employed" 09/28/2005 - "Administration of SSRI, zimelidine, citalopram and fluoxetine, 5-HT(2A,2C) receptor agonist, R(-)-DOI and the 5-HT2C receptor agonists, mCPP, and MK212 resulted in a marked increase in incidence of convulsions and a reduction in the threshold of lidocaine-induced convulsions, while the 5-HT2B receptor agonist, BW723C86, had little influence" Get all the results and reference details, order at left...
4.	Migraine Disorders (Migraine) 01/01/1998 - "A role for 5-HT2B receptors has also been suggested the initiation of migraine, supporting use of selective 5-HT2B receptor antagonists in migraine" 05/01/1999 - "1. Serotonin has been implicated as a mediator involved in migraine headache, an effect that may involve central 5-HT2B receptor activation" Get all the results and reference details, order at left...
5.	Hypertrophy 07/01/2003 - "We found that overexpression of 5-HT2B receptor in heart leads to ventricular hypertrophy as the result of increased cell number and size" 08/19/2003 - "Functional consequence of serotonin/5-HT2B receptor signaling in heart: role of mitochondria in transition between hypertrophy and heart failure?" Get all the results and reference details, order at left...
18 Diseases and 20 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Serotonin (5 Hydroxytryptamine)
2.	1- (5- (2- thenyloxy)- 1H- indol- 3- yl)propan- 2- amine
3.	Desoxycorticosterone (DOCA)
4.	SB 215505
5.	Interleukin-1beta (Interleukin 1 beta)
6.	5-HT2C Serotonin Receptor
7.	Dopamine Agonists (Dopamine Agonist)
8.	Interleukin-6 (Interleukin 6)
9.	Citalopram (Escitalopram)
10.	Zimeldine (Zimelidine)
19 Drugs and Important Bio-Agents and 13 more articles analyzed in the Research Interface, order at left...

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