5-HT2A Serotonin Receptor (5 HT2A Receptor)

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310 relevant articles (14 outcomes, 65 trials/studies) found for this Bio-Agent

Description: A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.

Also Known As:

5 HT2A Receptor; Receptor, Serotonin, 5-HT2A; 5-HT(2A) Receptor; 5-HT2A Receptor; Receptor, Serotonin 2A; Serotonin 2A Receptors; 2A Receptor, Serotonin; 2A Receptors, Serotonin; Receptor, 5-HT2A; Receptors, Serotonin 2A; Serotonin 2A Receptor

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 56522

Membrane Proteins: 4214

Cell Surface Receptors: 633

G-Protein-Coupled Receptors: 403

Serotonin Receptors: 406

5-HT2 Serotonin Receptors: 28

5-HT2A Serotonin Receptor: 310

Neurotransmitter Receptors: 266

Biogenic Amine Receptors: 3

Serotonin Receptors: 406

5-HT2 Serotonin Receptors: 28

5-HT2A Serotonin Receptor: 310

Biogenic Amine Receptors: 3

Serotonin Receptors: 406

5-HT2 Serotonin Receptors: 28

5-HT2A Serotonin Receptor: 310

Experts

1.	Hamon, Michel: 4 articles (07/2008 - 05/2002)
2.	Kennedy, James L: 4 articles (04/2007 - 08/2004)
3.	Knudsen, Gitte M: 3 articles (03/2008 - 09/2005)
4.	Pinborg, Lars H: 3 articles (03/2008 - 09/2005)
5.	Svarer, Claus: 3 articles (03/2008 - 09/2005)
6.	Gorwood, Philip: 3 articles (01/2008 - 05/2002)
7.	Boni, Claudette: 3 articles (01/2008 - 05/2002)
8.	Audenaert, Kurt: 3 articles (08/2007 - 02/2003)
9.	Goethals, Ingeborg: 3 articles (08/2007 - 02/2003)
10.	van Heeringen, Cees: 3 articles (08/2007 - 02/2003)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 01/01/1995 - "The limited clinical evidence available also suggests that compounds producing 5-HT2A receptor blockade are effective, in particular, against the negative symptoms of schizophrenia." 02/17/2006 - "Association study of serotonin 2A receptor (5-HT2A) gene with schizophrenia and suicidal behavior using systematic meta-analysis." 01/01/2003 - "AIM: In this study, we assessed the relationship of schizophrenia and its subgroups with 5-HT2A receptor gene polymorphism, and attempted to evaluate a possible correlation between the severity and prognosis of the illness and 5-HT2A receptor gene polymorphism" 10/30/2000 - "Several postmortem studies have reported regionally localized decreases in serotonin(2A) receptors (5-HT(2A)R) in schizophrenia" 02/07/2000 - "Recent studies have also shown an association between the allele C of 102T/C polymorphism in the 5-HT2A receptor gene and schizophrenia" Get all the results and reference details, order at left...
2.	Pain (Aches) 09/01/2002 - "5-HT2A receptor subtype in the peripheral branch of sensory fibers is involved in the potentiation of inflammatory pain in rats." 09/01/2001 - "We show the involvement of the 5-HT2A receptor activity in the inflammatory and neuropathic pain" 09/01/2001 - "Involvement of peripheral 5-HT2A receptor activation in inflammatory pain]" 05/04/2001 - "This result suggested that the synthesis of 5-HT2A receptor is enhanced in spinal dorsal horn, NRM, vlPAG and DRN during inflammatory pain." 05/20/2008 - "SUMMARY OF BACKGROUND DATA: In previous studies, 5-HT2A receptor antagonists improved sciatica in patients with LDH and attenuated pain-related behavior induced by nucleus pulposus applied to the nerve root in rats" Get all the results and reference details, order at left...
3.	Syndrome 12/01/2007 - "In addition, prior studies have shown polymorphisms in the serotonin 2A receptor (HTR2A) gene to be associated with two syndrome components, hypertension and central adiposity" 10/01/2001 - "Association of T102C polymorphism of the 5-HT2A receptor gene with psychiatric status in fibromyalgia syndrome." 09/01/2003 - "METHODS: Doses of the 5-HT(2A) receptor antagonists that were sufficient for receptor blockade were determined in 5-HT behavioural syndrome tests" 07/01/2003 - "This review describes the clinical syndrome of psychosis in PD and data regarding the efficacy and tolerability of existing antipsychotic agents, and presents the scientific rationale for the development of serotonin 2A receptor inverse agonists as potential therapeutic agents for treatment-induced psychosis of PD." 06/01/2003 - "AO (sequence 4) treatment allowed the identification of specific central 5-HT2A receptor-mediated behaviours in the complex serotonergic syndrome induced by tryptamine in rats" Get all the results and reference details, order at left...
4.	Autistic Disorder (Autism) 03/30/2007 - "Family-based association study of 5-HTTLPR and the 5-HT2A receptor gene polymorphisms with autism spectrum disorder in Korean trios." 01/01/2003 - "Serotonin 2A receptor gene polymorphism and clinical efficacy of fluvoxamine in children with autistic disorder]" 04/08/2002 - "This well-replicated finding and subsequent studies of platelet serotonin receptors in autism indicate that the serotonin 2A receptor gene (HTR2A) on chromosome 13q is a primary candidate gene in autism" 04/08/2002 - "Transmission disequilibrium studies of the serotonin 5-HT2A receptor gene (HTR2A) in autism." 03/30/2007 - "Promoter region polymorphisms (5-HTTLPR) of the serotonin transporter gene (SLC6A4) and the 5-HT2A receptor gene (HTR2A) have been studied as potential candidate genes in autism spectrum disorder (ASD)" Get all the results and reference details, order at left...
5.	Hyperglycemia 12/01/2007 - "The Influence of hyperactivity of the hypothalamic-pituitary-adrenal axis and hyperglycemia on the 5-HT2A receptor-mediated wet-dog shake responses in rats." 12/01/2000 - "Previous report demonstrated that the peripheral 5-HT2A receptor agonist induces hyperglycemia in rats but does not increase plasma glucagon levels at doses inducing hyperglycemia" 04/04/1997 - "These results suggest that 5-methoxytryptamine-induced hyperglycemia is mediated by the peripheral 5-HT2A receptor, although it has a high affinity for the 5-HT4 receptor" 10/01/1996 - "The 5-HT2A receptor antagonist, ketanserin, significantly inhibited alpha-methyl-5-HT-elicited hyperglycemia" 01/01/1995 - "The involvement of the peripheral 5-HT2A receptor in peripherally administered serotonin-induced hyperglycemia in rats." Get all the results and reference details, order at left...
131 Diseases and 310 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Serotonin (5 Hydroxytryptamine)
2.	sarpogrelate
3.	Antipsychotic Agents (Antipsychotics)
4.	nefazodone (Serzone)
5.	Ketanserin
6.	Ritanserin
7.	Risperidone (Risperdal Consta)
8.	Dizocilpine Maleate (Dizocilpine)
9.	Dopamine D3 Receptors
10.	Fluoxetine (Prozac)
167 Drugs and Important Bio-Agents and 191 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Lasers (Laser)
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)
3 Therapies and Procedures and 4 more articles analyzed in the Research Interface, order at left...

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