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5-HT1B Serotonin Receptor

A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.
Also Known As:
Receptor, Serotonin, 5-HT1B; 5-HT(1B) Receptor; 5-HT(1Dbeta) Receptor; 5-HT1B Receptor; 5-HT1Dbeta Receptor; 5-Hydroxytryptamine 1B Receptor; 5-Hydroxytryptamine 1B Receptors; Receptor, 5-Hydroxytryptamine 1B; Receptor, Serotonin Type 1Dbeta; Serotonin 1D Beta Receptor; Serotonin 1Dbeta Receptor; Serotonin 1Dbeta Receptors; 1B Receptor, 5-Hydroxytryptamine; 1B Receptor, Serotonin; 1B Receptors, 5-Hydroxytryptamine; 1Dbeta Receptor, Serotonin; 1Dbeta Receptors, Serotonin; 5 HT1B Receptor; 5 HT1Dbeta Receptor; 5 Hydroxytryptamine 1B Receptor; 5 Hydroxytryptamine 1B Receptors; Receptor, 5 Hydroxytryptamine 1B; Receptor, 5-HT1B; Receptor, 5-HT1Dbeta; Receptor, Serotonin 1B; Receptor, Serotonin 1Dbeta; Receptors, 5-Hydroxytryptamine 1B; Receptors, Serotonin 1Dbeta; Serotonin 1B Receptor
Networked: 94 relevant articles (2 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Svenningsson, Per: 3 articles (07/2015 - 02/2008)
2. MaassenVanDenBrink, Antoinette: 3 articles (10/2009 - 05/2007)
3. Kennedy, J L: 3 articles (01/2003 - 07/2000)
4. Hen, R: 3 articles (11/2001 - 09/2000)
5. Forsberg, Anton: 2 articles (07/2015 - 08/2014)
6. Varrone, Andrea: 2 articles (07/2015 - 08/2014)
7. Halldin, Christer: 2 articles (07/2015 - 08/2014)
8. Farde, Lars: 2 articles (07/2015 - 08/2014)
9. Neisewander, Janet L: 2 articles (03/2014 - 09/2012)
10. Pentkowski, Nathan S: 2 articles (03/2014 - 09/2012)

Related Diseases

1. Migraine Disorders (Migraine)
2. Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
3. Pain (Aches)
4. Schizophrenia (Dementia Praecox)
5. Parkinson Disease (Parkinson's Disease)

Related Drugs and Biologics

1. Sumatriptan (Imigran)
2. MAP Kinase Kinase 1
3. Endothelins (Endothelin)
4. Serotonin (5 Hydroxytryptamine)
5. Levodopa (L Dopa)
6. Ethanol (Ethyl Alcohol)
7. 5-HT2C Serotonin Receptor
8. Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)
9. Melanocortin Receptors (Melanocortin Receptor)
10. Dopamine D2 Receptors (Dopamine D2 Receptor)

Related Therapies and Procedures

1. Therapeutics
2. Self Administration (Administration, Self)