|1.||Colpaert, Francis C: 10 articles (07/2007 - 10/2002)|
|2.||Kasper, Siegfried: 9 articles (11/2014 - 06/2002)|
|3.||Bishop, Christopher: 9 articles (11/2013 - 05/2006)|
|4.||Koek, W: 7 articles (09/2015 - 04/2000)|
|5.||Kline, Anthony E: 7 articles (12/2014 - 11/2002)|
|6.||Mitterhauser, Markus: 7 articles (11/2014 - 05/2007)|
|7.||Lanzenberger, Rupert: 7 articles (11/2014 - 12/2008)|
|8.||Wadsak, Wolfgang: 7 articles (11/2014 - 05/2007)|
|9.||Dupre, Kristin B: 7 articles (11/2013 - 07/2007)|
|10.||Uphouse, Lynda: 7 articles (02/2013 - 06/2002)|
|1.||Schizophrenia (Dementia Praecox)
01/01/2015 - "This study aimed to explore the influence of two genetic polymorphisms of the 5-hydroxytryptamine 1A receptor (5-HT1A) and solute carrier family 6, member 4 (SLC6A4) genes on the clinical symptoms and treatment resistance in Slovenian patients with schizophrenia. "
12/16/2008 - "Further study is needed to determine the role of the 5-HT(1A) receptor to improve cognitive function in schizophrenia."
12/01/2006 - "Postmortem and positron emission tomography (PET) studies have reported several alterations in serotonin 1A receptor (5-HT(1A)) binding parameters in patients with schizophrenia. "
03/01/2001 - "In patients with schizophrenia, the majority of post-mortem studies have reported increases in 5-HT1A receptor density in the prefrontal cortex in the approximate range 15-80%. "
07/01/2000 - "The above results of preclinical investigations indicate that 5-HT1A receptor can be involved in the pathology of schizophrenia, what is partly confirmed by clinical postmortem studies of schizophrenic brains. "
|2.||Brain Injuries (Brain Injury)
05/01/2002 - "They also indicate that injury-induced changes in the 5-HT1A receptor may contribute to traumatic brain injury-induced cognitive deficits."
01/01/2001 - "The selective 5-HT(1A) receptor agonist repinotan HCl attenuates histopathology and spatial learning deficits following traumatic brain injury in rats."
01/01/2001 - " findings extend the therapeutic efficacy of Repinotan HCl to a contusion model of experimental brain injury and demonstrate for the first time that 5-HT(1A) receptor agonists confer neuroprotection and attenuate spatial learning deficits following controlled cortical impact injury. "
04/01/2005 - "Neuroprotective efficacy of repinotan HCl, a 5-HT1A receptor agonist, in animal models of stroke and traumatic brain injury."
04/01/2005 - "Repinotan is a highly potent 5-HT1A receptor agonist with strong neuroprotective efficacy in animal models of middle cerebral artery occlusion and traumatic brain injury. "
|3.||Anxiety Disorders (Anxiety Disorder)
06/01/2014 - "The results strongly suggest that 5-HT1A receptor partial agonists would be useful and beneficial in the treatment of depressive and anxiety disorders through increased hippocampal neurogenesis."
07/05/2008 - "Association study between the serotonin 1A receptor (HTR1A) gene and neuroticism, major depression, and anxiety disorders."
05/01/2007 - "The objective of this study was to investigate 5-HT1A receptor binding potential (BP) in social anxiety disorder (SAD). "
01/16/2013 - "Of these, the 5-HT(1A) receptor subtype, which was the first to be cloned and characterized, has received considerable attention based on its purported role in the etiology and treatment of mood and anxiety disorders. "
01/01/2012 - "The results suggest that activation of the 5-HT(1A) receptor can potentiate the effect of CRF on endophenotypes of anxiety disorders in animal models. "
09/06/2012 - "The objective of this study was to systematically examine the mechanism and site of action of a selective 5-HT(1A) receptor agonist 8-hydroxy-2-(di-n-propylamino)-tetralin (DPAT) on visceral pain. "
01/01/1989 - "Although further studies are required, these preliminary data support 5-HT1A receptor involvement in the mediation of this form of adaptive pain inhibition."
01/01/2014 - "These findings suggest that the 5-HT(1A) receptor is a potential target molecule for treatment of psychiatric disorders and pain."
05/01/2013 - "These findings suggest that isolation rearing causes hypoalgesia in mouse models of acute pain and imply that the spinal 5-HT1A receptor activation probably through descending serotonergic inhibitory pathway is involved in isolation rearing-induced hypoalgesia."
01/01/2012 - "Accordingly, variation in the 5-HT1A receptor gene (HTR1A) may contribute to inter-individual differences in human pain sensitivity. "
02/25/2003 - "An association between 5-HT(1A) receptor availability in the raphe and severity of parkinsonian tremor was also found."
12/01/2007 - "CB(1) knockout animals exhibited a significant reduction in the induction of head twitches and paw tremor by the 5-HT(2A/C) receptor selective agonist (+/-) DOI, as well as a reduced hypothermic response following administration of the 5-HT(1A) receptor agonist (+/-)-8-OH-DPAT. "
11/10/2000 - "These findings suggest that nicotine-induced tail tremor is mediated by 5-HT(1A) receptors and that 5-HT(1A) receptor antagonists are effective in the treatment of tremor."
11/10/2000 - "Tail tremor induced by nicotine (0.5 mg/kg, s.c.) was suppressed by a 5-HT(1A) receptor antagonist, N-¿2-[4-(2-methoxyphenyl)-1-piperazinyl-]ethyl¿-N-(2-pyridinyl)cycloh exanecarboxamide trihydrochloride (WAY-100635; 0.3-3 mg/kg, i.p.), but not by a 5-HT(2) receptor antagonist, ketanserin (0.1-0.3 mg/kg, i.p). "
11/10/2000 - "The 5-HT(1A) receptor agonists, buspirone (1-20 mg/kg, i.p.), gepirone (1-10 mg/kg, i.p.), tandospirone (1-10 mg/kg, i.p.) and (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT; 0.01-0.1 mg/kg, s.c.), enhanced the tail tremor. "
|1.||Serotonin (5 Hydroxytryptamine)
|8.||Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)
|10.||Antipsychotic Agents (Antipsychotics)
|5.||Drug Therapy (Chemotherapy)