|1.||Miao, Yubin: 18 articles (04/2015 - 11/2003)|
|2.||Yang, Jianquan: 9 articles (04/2015 - 08/2009)|
|3.||Guo, Haixun: 9 articles (12/2014 - 08/2009)|
|4.||García-Borrón, José C: 9 articles (12/2012 - 04/2005)|
|5.||Jiménez-Cervantes, Celia: 9 articles (12/2012 - 12/2002)|
|6.||Gallazzi, Fabio: 8 articles (01/2015 - 05/2009)|
|7.||Berwick, Marianne: 6 articles (06/2015 - 05/2004)|
|8.||Kanetsky, Peter A: 6 articles (06/2015 - 07/2005)|
|9.||Quinn, Thomas P: 6 articles (01/2015 - 11/2003)|
|10.||Cheng, Zhen: 6 articles (03/2014 - 05/2007)|
|1.||Melanoma (Melanoma, Malignant)
09/15/2010 - "Substitution of the Lys linker with an Arg linker dramatically improved the melanoma uptake and reduced the renal uptake of 99mTc-RGD-Arg-(Arg11)CCMSH, warranting the further evaluation of 188Re-labeled RGD-Arg-(Arg11)CCMSH as a novel MC1 receptor-targeting therapeutic peptide for melanoma treatment in the future."
10/01/2011 - "Polymorphisms in the melanocortin 1 receptor (MC1R) gene have been associated with increased risks of melanoma, but different approaches to study design, analysis, and reporting have hindered comparisons of findings. "
10/15/2009 - "Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations."
10/01/2008 - "Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. "
09/15/2006 - "Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma."
|2.||Basal Cell Carcinoma (Rodent Ulcer)
07/01/2006 - "In this study, we assessed the role of melanocortin 1 receptor (MC1R) variants and of two patched (PTCH) polymorphisms (c.3944C>T (P1315L), insertion 18 bp IVS1-83) as risk factors for basal cell carcinoma (BCC) in the French population. "
06/01/2015 - "Melanocortin 1 receptor (MC1R) gene variants are a major contributor to pigmentation characteristics and the modulation of sporadic basal cell carcinoma (BCC) risk. "
05/01/2010 - "Other genes of importance to basal cell carcinoma development include the tumour suppressor gene P53 and the melanocortin-1 receptor gene. "
02/01/2009 - "In this study, we assessed the role of melanocortin-1 receptor (MC1R) and agouti signalling protein (ASIP) polymorphisms in cutaneous melanoma and basal cell carcinoma (BCC) development in a Polish population. "
12/01/2015 - "With comprehensive data on pigment characteristics, lifestyle factors, and melanocortin 1 receptor (MC1R) gene sequence, we sought to clarify the role of family history of skin cancer in early-onset basal cell carcinoma (BCC). "
|3.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/01/2001 - "Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma."
05/01/2004 - "The authors quantified improvement in predicting cutaneous malignant melanoma, basal cell carcinoma, and squamous cell carcinoma of the skin made possible by information on common variants of the melanocortin-1 receptor gene (MC1R) in a 1998-1999 population-based case-control study of subjects aged 20-59 years of northern European ancestry in Tasmania, Australia. "
10/01/2015 - "In biodistribution studies, a receptor-specific uptake was observed in MC1 receptor-positive organs so that after 2 h the uptake in mouse tumor was 5.10 ± 0.08 % ID/g, while low accumulation in the kidney uptake was observed (4.58 ± 0.68 % ID/g at 2 h after injection). "
09/01/2015 - "Overall, our observations suggest that BCCs are part of the BAP1 cancer syndrome, perhaps in relation with chronic sun exposure and melanocortin 1 receptor (MC1R) variants. "
04/01/2013 - "Tumor samples were analyzed for melanocortin-1 receptor (MC1R) variants and mutations in the BRAF and NRAS genes. "
01/01/2013 - "Polymorphisms of the melanocortin 1 receptor (MC1R) gene, in particular, correlate with fairness of skin, UV sensitivity, and enhanced cancer risk. "
01/01/2011 - "Melanocortin 1 receptor (MC1R), a Gs protein-coupled receptor expressed in melanocytes, is a major determinant of skin pigmentation, phototype and cancer risk. "
|5.||Oculocutaneous Albinism (Albinism, Yellow Mutant)
08/01/2007 - "In this study, two coding SNPs, c.G1129A (R163Q) at the MC1R (melanocortin 1 receptor) gene and c.A1962G (H615R) at the OCA2 (oculocutaneous albinism type II) gene, were investigated in a total of 1,809 individuals in 16 populations from various areas. "
01/01/2015 - "To address this need, we designed transcription activator-like effector nucleases (TALENs) to target two genes that contain coding changes in cavefish relative to surface fish and map to the same location as QTL for pigmentation, oculocutaneous albinism 2 (oca2) and melanocortin 1 receptor (mc1r). "
06/01/2001 - "The melanocortin-1 receptor (MC1R) and P gene product are two important components of the human pigmentary system that have been shown to be associated with red hair/fair skin and cause type II oculocutaneous albinism, respectively. "
02/01/2010 - "We have previously described the role of red hair (melanocortin-1 receptor, MC1R) and blue eye (oculocutaneous albinism type II, OCA2) gene polymorphisms in modulating the risk of cutaneous malignant melanoma (CMM) in a highly sun-exposed population of European descent. "
02/01/2011 - "Melanocortin 1 receptor (MC1R) is involved in various functions, such as pigmentation, antipyretic and anti-inflammatory actions, development of melanoma, susceptibility to ultraviolet-induced sun damage, modification of oculocutaneous albinism, development of freckles, and mediation of female-specific mechanisms of analgesia. "
|3.||Microphthalmia-Associated Transcription Factor
|4.||Monophenol Monooxygenase (Tyrosinase)
|5.||Melanocyte-Stimulating Hormones (MSH)
|7.||Endothelin-3 (Endothelin 3)
|8.||Stem Cell Factor