|1.||Wang, Ji Ming: 21 articles (11/2014 - 01/2002)|
|2.||Gong, Wanghua: 15 articles (09/2011 - 01/2002)|
|3.||Iribarren, Pablo: 10 articles (07/2007 - 11/2003)|
|4.||Chen, Keqiang: 9 articles (09/2011 - 11/2005)|
|5.||Perretti, Mauro: 8 articles (12/2014 - 11/2003)|
|6.||Bae, Yoe-Sik: 7 articles (04/2015 - 10/2003)|
|7.||Le, Yingying: 7 articles (01/2005 - 01/2002)|
|8.||Ryu, Sung Ho: 6 articles (04/2015 - 10/2003)|
|9.||Hu, Jinyue: 6 articles (02/2006 - 10/2004)|
|10.||Flower, Roderick J: 5 articles (12/2014 - 01/2009)|
|1.||Asthma (Bronchial Asthma)
02/01/2015 - "The D prostanoid receptor 2 (DP2; also known as chemoattractant receptor-homologous molecule expressed on TH2 cells) is implicated in the pathogenesis of asthma, but its expression within bronchial biopsy specimens is unknown. "
02/01/2013 - "The D-prostanoid receptor and the chemoattractant receptor homologous molecule expressed on T(H)2 cells (CRTH2) are implicated in asthma pathogenesis. "
07/01/2009 - "Genetic variations in chemoattractant receptor expressed on Th2 cells (CRTH2) is associated with asthma susceptibility in Chinese children."
01/01/2007 - "Genetic impact of functional single nucleotide polymorphisms in the 3'-UTR region of the chemoattractant receptor expressed on Th2 cells (CRTH2) gene on asthma and atopy in a Japanese population."
11/01/2004 - "Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability."
|2.||Bacterial Infections (Bacterial Infection)
11/01/2002 - "This suggests that the formyl-peptide receptor (FPR) and its variant FPRL1 (FPR-like 1) are involved in host defense against bacterial infection and in the clearance of damaged cells. "
06/15/2004 - "The human N-formyl peptide receptor (FPR) is a key modulator of chemotaxis directing granulocytes toward sites of bacterial infections. "
07/01/2006 - "This indicates that formyl peptide receptor may be important in viral infections and that variations in its sequence among individuals may affect their likelihood of viral and bacterial infections."
02/01/2008 - "Formyl peptide receptor (FPR) and C5a receptor (C5aR) are chemoattractant G protein-coupled receptors (GPCRs) involved in the innate immune response against bacterial infections and tissue injury. "
01/03/2005 - "Formyl peptide receptor (FPR) and FPR-like receptor (FPRL)1, two G protein-coupled receptors belonging to the FPR family, play an essential role in host defense mechanisms against bacterial infection and in the regulation of inflammatory reactions. "
12/01/2013 - "Setipiprant, a tetrahydropyridoindole derivative, is a CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper [Th]-2 cells) antagonist that has the potential to be effective in the treatment of patients with diseases with an allergic etiology, such as allergic rhinitis and asthma. "
07/01/2005 - "The discovery of a second receptor for prostaglandin D2, chemoattractant receptor-homologous molecule expressed on T helper type 2 (CRTH2), has revived significant efforts into the development of small-molecule antagonists for allergic diseases as the receptor is predominantly expressed on cells such as eosinophils, TH2 cells and basophils, which are major pro-inflammatory cells in diseases such as asthma and allergic rhinitis. "
01/01/2011 - "The chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) is a G protein-coupled receptor that has been reported to modulate inflammatory responses in various rodent models of asthma, allergic rhinitis and atopic dermatitis. "
12/01/2014 - "Chemoattractant receptor-homologous molecule expressed on T helper (Th) 2 cells (CRTH2) is a G-protein-coupled receptor for prostaglandin D2 (PGD2), a key mediator in inflammatory disorders such as asthma and allergic rhinitis. "
01/01/2011 - "Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice."
11/01/2015 - "The anti-inflammatory protein annexin A1 (AnxA1) and its formyl peptide receptor 2 (FPR2) have protective effects in organ fibrosis. "
03/01/2014 - "These included three antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2), which had been evaluated in allergic respiratory disease and (in one case) chronic obstructive pulmonary disease (COPD), and other agents intended for the treatment of asthma, COPD, pulmonary hypertension and lung fibrosis. "
|5.||Seasonal Allergic Rhinitis (Hay Fever)
02/01/2014 - "Efficacy of the oral chemoattractant receptor homologous molecule on TH2 cells antagonist BI 671800 in patients with seasonal allergic rhinitis."
02/01/2014 - "The inflammatory response in patients with seasonal allergic rhinitis (SAR) is partly mediated by the prostaglandin D2 receptor chemoattractant receptor homologous molecule on T(H)2 cells (CRTH2). "
|1.||GTP-Binding Proteins (G-Protein)
|6.||4- butoxy- N- (2- (4- methoxy- phenyl)- 4- oxo- 1,4- dihydro- 2H- quinazolin- 3- yl)- benzamide
|7.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|8.||prostaglandin D2 receptor
|3.||Drug Therapy (Chemotherapy)