|1.||Fallon, Michael B: 7 articles (06/2014 - 05/2003)|
|2.||Gulati, Anil: 6 articles (08/2013 - 11/2004)|
|3.||Yanagisawa, Masashi: 6 articles (08/2006 - 04/2002)|
|4.||Yanagisawa, M: 6 articles (01/2004 - 04/2000)|
|5.||Zhang, Junlan: 5 articles (06/2014 - 05/2003)|
|6.||Luo, Bao: 5 articles (04/2009 - 05/2003)|
|7.||Wülfing, Pia: 5 articles (08/2007 - 09/2003)|
|8.||Papalois, Apostolos: 4 articles (01/2015 - 03/2010)|
|9.||Kolettis, Theofilos M: 4 articles (01/2015 - 03/2010)|
|10.||Kyriakides, Zenon S: 4 articles (01/2015 - 03/2010)|
|1.||Pulmonary Hypertension (Ayerza Syndrome)
01/01/2013 - "A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model."
12/01/2005 - "Endothelin-B receptor overexpression prevents hypoxic pulmonary hypertension in cirrhotic rats."
04/01/2002 - "Exaggerated hypoxic pulmonary hypertension in endothelin B receptor-deficient rats."
03/05/2002 - "Selective upregulation of endothelin B receptor gene expression in severe pulmonary hypertension."
10/01/2000 - "Prolonged endothelin B receptor blockade causes pulmonary hypertension in the ovine fetus."
|2.||Breast Neoplasms (Breast Cancer)
11/01/2004 - "Endothelin-1-induced vasodilatation in rat breast tumor is mediated through endothelin-B receptors."
08/01/2009 - "Stromal endothelin B receptor-deficiency inhibits breast cancer growth and metastasis."
04/01/2004 - "Endothelin-1-, endothelin-A-, and endothelin-B-receptor expression is correlated with vascular endothelial growth factor expression and angiogenesis in breast cancer."
09/15/2003 - "Expression of endothelin-1, endothelin-A, and endothelin-B receptor in human breast cancer and correlation with long-term follow-up."
05/15/2007 - "IRL-1620, a potent endothelin B receptor agonist, enhanced the efficacy of paclitaxel in a breast tumor model, but its effect in prostate cancer is not known. "
04/01/2014 - "Recently, it was reported that the endothelin B receptor (ETBR) of tumor endothelial cells prevents antitumor immunity. "
07/15/2009 - "In this review, we discuss a novel role of the endothelin-B-receptor (ET(B)R) in tumorigenesis and the effect of its blockade during cancer immune therapy. "
07/15/2009 - "Endothelin B receptor, a new target in cancer immune therapy."
01/01/2008 - "Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy."
11/01/2004 - "Results indicate that ET-1 induced an increase in blood flow to tumors in tumor-bearing rats, which is mediated by endothelin-B receptors."
02/01/2005 - "We induced cirrhosis in male Sprague-Dawley rats using common bile duct ligation (CBDL) and exposed them to CH (inspired PO2 approximately 76 Torr) or maintained them in Denver (Den, inspired PO2 approximately 122 Torr) for 3 wk. Our data show 1) CBDL-CH rats had a persistent blunted hypoxic pulmonary vasoconstriction similar to CBDL-Den; 2) the development of hypoxic pulmonary hypertension was completely prevented in the CBDL-CH rats, as indicated by normal pulmonary arterial pressure and lack of right ventricular hypertrophy and pulmonary arteriole remodeling; and 3) selective increases in expression of ET-1, pulmonary endothelin B receptor, eNOS, and heme oxygenase 1 are potential mechanisms of protection against hypoxic pulmonary hypertension in the CBDL-CH rats. "
01/15/2002 - "In the present study, laser-captured microdissection was performed in regions of WIBC-9 tumors that exhibited VM without endothelial cells, central necrosis, or fibrosis, revealing expression of human-Flt-1 and human-Tie2 and the absence of human-CD31, human-endothelin B receptor, and human-thrombin receptor. "
|5.||Melanoma (Melanoma, Malignant)
06/01/2014 - "MAPK pathway inhibition enhances the efficacy of an anti-endothelin B receptor drug conjugate by inducing target expression in melanoma."
03/01/2011 - "An antibody-drug conjugate targeting the endothelin B receptor for the treatment of melanoma."
11/01/2004 - "Endothelin-B receptor blockade inhibits molecular effectors of melanoma cell progression."
02/15/2004 - "Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression."
06/01/1999 - "Downregulation of endothelin B receptor in human melanoma cell lines parallel to differentiation genes."
|4.||Nitric Oxide (Nitrogen Monoxide)
|7.||Endothelin Receptors (Endothelin Receptor)
|8.||N- (5- (4- bromophenyl)- 6- (2- (5- bromopyrimidin- 2- yloxy)ethoxy)pyrimidin- 4- yl)- N'- propylaminosulfonamide
|9.||Endothelin-1 (Endothelin 1)
|10.||Endothelin A Receptor
|4.||Transurethral Resection of Prostate (TURP)