|1.||Antkiewicz-Michaluk, Lucyna: 2 articles (01/2003 - 11/2002)|
|2.||Neuenschwander, Kent: 1 article (03/2013)|
|3.||Dwyer, Shannon: 1 article (03/2013)|
|4.||Moorcroft, Neil D: 1 article (03/2013)|
|5.||Gao, Zhongli: 1 article (03/2013)|
|6.||Davis, Larry: 1 article (03/2013)|
|7.||Giovanni, Andrew: 1 article (03/2013)|
|8.||Roehr, Joachim: 1 article (03/2013)|
|9.||Scotese, Anthony: 1 article (03/2013)|
|10.||Ramagiri, Suma: 1 article (05/2008)|
|1.||Alcoholism (Alcohol Abuse)
05/01/1996 - "Tetrahydroisoquinolines and alcoholism: where are we today?"
01/01/1992 - "[Tetrahydroisoquinolines--endogenous products from chronic alcohol abuse]."
05/01/1991 - "This decrease can be cause by the chronic alcohol intake, and can be mediated by the tetrahydroisoquinolines (TIQs) or otherwise be the cause and not the consequence of alcoholism. "
04/01/1978 - "Tetrahydroisoquinolines in the brain: the basis of an animal model of alcoholism."
07/01/2003 - "Our data can serve as reference for other studies in humans concerning the etiology of alcoholism or other neurodegenerative diseases with the involvement of tetrahydroisoquinolines."
|2.||Neurodegenerative Diseases (Neurodegenerative Disease)
|3.||Parkinson Disease (Parkinson's Disease)
09/15/2000 - "1,2,3,4-Tetrahydroisoquinolines are considered to play an essential role as neurotoxic compounds in the pathomechanism of Parkinson's disease. "
09/15/2000 - "Development of a method for sample preparation for subsequent identification and measurement of 1,2,3,4-tetrahydroisoquinolines and other potentially neurotoxic compounds by high-performance liquid chromatography with ultraviolet and fluorescence detection in blood plasma of Parkinson's disease patients."
01/01/2000 - "The finding that endogenous tetrahydroisoquinolines may be involved in the etiology of Parkinson's disease suggests that their administration may cause changes resembling those observed in parkinsonian brain. "
12/01/1989 - "[Tetrahydroisoquinolines in connection with Parkinson's disease]."
05/01/2008 - "N-methyl-norsalsolinol and related tetrahydroisoquinolines accumulate in the nigrostriatal system of the human brain and are increased in the cerebrospinal fluid of patients with Parkinson's disease. "
09/15/1988 - "This paper describes experiments designed to evaluate whether the narcotic antagonist naloxone significantly interferes with seizures induced by tetrahydroisoquinolines (TIQs). "
01/01/2004 - "The anticonvulsant activity of competitive 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F)-quinoxaline (NBQX) and noncompetitive 2,3-benzodiazepines and tetrahydroisoquinolines (THIQs) AMPA/kainate receptor antagonists, was tested in different experimental seizure models and compared with diazepam, a conventional antiepileptic drug acting on GABAergic neurotransmission. "
|5.||Schizophrenia (Dementia Praecox)
03/01/2013 - "A series of tetrahydroisoquinolines were designed, synthesized and evaluated as the first non-natural product type of compounds with dual D(1) receptor (D(1)R) agonism and D(2) receptor (D(2)R) antagonism properties for treatment of schizophrenia. "
05/01/1981 - "The present results open the possibility that the in vivo formation of tetrahydroisoquinolines could be involved in some mental pathologies, such as schizophrenia, as has been previously suggested."
|4.||1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
|5.||Serotonin (5 Hydroxytryptamine)
|9.||alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)
|10.||Kainic Acid Receptors (Kainate Receptor)