Angiogenesis Inducing Agents (Angiogenesis Factor)

Agents that induce or stimulate PHYSIOLOGIC ANGIOGENESIS or PATHOLOGIC ANGIOGENESIS.

Also Known As:

Angiogenesis Factor; Angiogenesis Effect; Angiogenesis Effects; Angiogenesis Stimulating Agents; Angiogenesis Stimulators; Angiogenic Factor; Tumor Angiogenic Factor; Agents, Angiogenesis Inducing; Agents, Angiogenesis Stimulating; Angiogenic Factor, Tumor; Effect, Angiogenesis; Effects, Angiogenesis; Factor, Angiogenesis; Factor, Angiogenic; Factor, Tumor Angiogenic; Inducers, Angiogenesis; Inducing Agents, Angiogenesis; Stimulating Agents, Angiogenesis; Stimulators, Angiogenesis; Angiogenesis Inducers

Networked: 1794 relevant articles (17 outcomes, 163 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Physiological Effects of Drugs: 1
    - Growth Substances: 16
      - Angiogenesis Modulating Agents: 14
        Angiogenesis Inducing Agents: 1794

Experts

1.	Karumanchi, S Ananth: 17 articles (03/2022 - 02/2004)
2.	Rana, Sarosh: 13 articles (03/2022 - 09/2008)
3.	Li, Wei: 10 articles (01/2022 - 07/2008)
4.	Furukawa, Tatsuhiko: 10 articles (01/2018 - 03/2002)
5.	Salahuddin, Saira: 10 articles (01/2018 - 05/2010)
6.	Ikeda, Ryuji: 10 articles (09/2013 - 03/2002)
7.	Yoshiji, Hitoshi: 10 articles (08/2010 - 03/2002)
8.	Fukui, Hiroshi: 9 articles (08/2010 - 03/2002)
9.	Ikenaka, Yasuhide: 9 articles (08/2010 - 12/2003)
10.	Noguchi, Ryuichi: 9 articles (08/2010 - 12/2003)

Related Diseases

1.	Neoplasms (Cancer) 04/30/2009 - "We conclude that in mice hVEGF-D is an angiogenic factor associated with improved muscle regeneration after ischemic injury but also with increased incidence of tumor formation with a preference for mammary gland tumors." 01/01/2023 - "In this study, we observed increased expression of the angiogenic-factor, Robo1 predominantly expressed on the blood vessels of B16F0 tumor. " 01/01/2022 - "Consequently, we expanded our previous study on the immune microenvironment of HCC and analyzed the relationship among the immune microenvironment, inflammatory/angiostatic factor expression, angiogenic factor expression, and tumor vessel findings, including vessels encapsulating tumor clusters (VETC) and macrotrabecular-massive (MTM) patterns. " 09/20/2015 - "In this study, the anti-tumor angiogenesis effects of CMCS were evaluated in vitro and in vivo. " 01/01/2014 - "Study outcomes included cancer cell proliferation rates and angiogenic factor secretion from cancer cells. "
2.	Ischemia 01/01/2018 - "BubR1 may be a crucial angiogenic factor and might be beneficial for the treatment of limb ischemia." 01/01/2016 - "However, the pro-angiogenesis effect of MSC-EVs in ischemia-reperfusion induced kidney injury and its potential mechanisms have yet to be determined. " 04/10/2014 - "Nrf2 regulates angiogenesis: effect on endothelial cells, bone marrow-derived proangiogenic cells and hind limb ischemia." 01/01/2012 - "Angiogenic factor AGGF1 promotes therapeutic angiogenesis in a mouse limb ischemia model." 06/01/2010 - "Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia."
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 10/01/2009 - "Our work thus advocates that the major function of VEGF-B is to act as a "survival", rather than an "angiogenic" factor and implicates a therapeutic potential of VEGF-B in treating different types of vascular and neurodegenerative diseases." 01/01/2021 - "SHED and its conditioned media can be effective in neurodegeneration through multiple mechanisms, including cell replacement, paracrine effects, angiogenesis, synaptogenesis, immunomodulation, and apoptosis inhibition, and SHED exosomes offer an ideal refined bed-to-bench formulation in neurodegenerative disorders. " 05/06/2011 - "Vascular endothelial growth factor-A (VEGF-A) is an angiogenic factor with neuroprotective effects that has been associated with neurodegenerative diseases. " 09/15/2016 - "Catalpol is the main active component of the radix from Rehmannia glutinosa Libosch, which has pleiotropic protective effects in neurodegenerative diseases, ischemic stroke, metabolic disorders and others Catalpol has been shown to have neuroprotective, neurorepair, and angiogenesis effects following ischemic brain injury. "
4.	Breast Neoplasms (Breast Cancer) 07/01/2009 - "During pregnancy, there was a general increase in each angiogenic factor, but degree of increase from one sampling period to the next was not associated with later breast cancer risk. " 02/01/2007 - "Correlation between P53 expression and CD34 angiogenic factor in Tunisian breast cancer." 03/01/2006 - "Here, we show that ectopic PAR1 expression induces expression of the angiogenic factor Cyr61(CCN1) in breast cancer cells. " 06/01/2003 - "The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives." 10/01/1998 - "We also measured the serum angiogenic factor levels in 34 operable breast cancer patients and compared them to those of healthy volunteer controls. "
5.	Wounds and Injuries (Trauma) 05/01/2014 - "The goal of the current study was to investigate the angiogenic factor levels prior to and following NPWT in infected wounds. " 01/01/2022 - "Among most factors related to wound healing, M2 macrophages will be recruited to the wound area and play a pivotal role in a time-limiting factor, angiogenesis. " 10/07/2019 - "Moreover, this pro-angiogenesis effect of DNIC-1 restores the impaired angiogenesis in the ischemic hind limb and accelerates the recovery rate of wound closure in diabetic mice. " 01/01/2019 - "Results: Compared with the control feet, nanofat-treated feet had significantly smaller wound areas at 7 and 9 days after grafting and showed better re-epithelialization, a greater number of microvessels and higher levels of angiogenic factor expression. " 01/01/2018 - "PEDF, an endogenous anti-angiogenic factor, is produced in wounds and may contribute to the removal of capillaries during wound resolution. "

Related Drugs and Biologics

1.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2.	Intercellular Signaling Peptides and Proteins (Growth Factors)
3.	Bevacizumab (Avastin)
4.	Collagen
5.	Apelin
6.	Angiostatins
7.	Interleukin-2 (IL2)
8.	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)
9.	Conditioned Culture Media
10.	Angiotensin II

Related Therapies and Procedures

1.	Immunotherapy
2.	Transplantation
3.	Immunomodulation
4.	Therapeutics
5.	Drug Therapy (Chemotherapy)