|1.||Wang, Dong: 4 articles (12/2011 - 06/2004)|
|2.||Silber, John R: 3 articles (06/2015 - 09/2002)|
|3.||Mitra, Sankar: 3 articles (01/2013 - 03/2008)|
|4.||Bohr, Vilhelm A: 2 articles (10/2015 - 01/2007)|
|5.||Madhusudan, Srinivasan: 2 articles (12/2014 - 08/2010)|
|6.||Yang, Xiaoming: 2 articles (10/2014 - 06/2005)|
|7.||Ramotar, Dindial: 2 articles (10/2014 - 06/2005)|
|8.||Tell, Gianluca: 2 articles (03/2014 - 11/2010)|
|9.||Bhakat, Kishor K: 2 articles (01/2013 - 03/2008)|
|10.||Wilson, David M: 2 articles (04/2012 - 01/2007)|
01/13/2009 - "Furthermore, inhibition of AP endonuclease may be effective in decreasing the dose requirements of chemotherapeutics used in the treatment of cancer as well as other diseases. "
06/01/2010 - "Using this platform, we have quantified DNA repair capacities of individuals with different genetic backgrounds, and compared the efficacy of potential cancer chemotherapeutics as inhibitors of a critical DNA repair enzyme, human AP endonuclease. "
01/01/2014 - "Previous studies have noted the induction of endoplasmic reticulum stress or apurinic endonuclease 1 (APE1) expression in many tumors. "
06/01/2015 - "Apurinic endonuclease 1 (Ape1), an enzyme in the base excision repair pathway, has been implicated in radiation resistance in cancer. "
04/28/2015 - "To evaluate the relationship between apurinic endonuclease 1 (APE1) Asp148Glu polymorphism and the susceptibility to gastrointestinal (GI) cancers. "
05/01/1997 - "Human apurinic endonuclease 1 expression in a colorectal adenoma-carcinoma sequence."
04/01/2012 - "Study of AP endonuclease (APEX1/REF1), a DNA repair enzyme, in gallbladder carcinoma."
11/01/1999 - "The present study examined the immunohistochemical expression of human AP endonuclease 1 (HAP1/Ref-1), the major endonuclease in the repair of apurinic/apyrimidinic (AP) sites in cellular DNA, in normal lung and lung carcinomas. "
06/18/2010 - "We now report that BRCA1 stimulates the base excision repair pathway, a major mechanism for the repair of oxidized DNA, by stimulating the activity of key base excision repair (BER) enzymes, including 8-oxoguanine DNA glycosylase (OGG1), the DNA glycosylase NTH1, and the apurinic endonuclease redox factor 1/apurinic endonuclease 1 (REF1/APE1), in human breast carcinoma cells. "
|3.||Myocardial Ischemia (Ischemic Heart Diseases)
|4.||Colorectal Neoplasms (Colorectal Cancer)
02/01/2004 - "[Study on significance of single nucleotide polymorphisms in the redox domain of aprimidinic/apurinic endonuclease/redox factor-1 gene in Chinese sporadic colorectal cancer]."
02/01/2004 - "To investigate the relationship between the single nucleotide polymorphisms(SNPs) in the redox domain of aprimidinic/apurinic endonuclease/redox factor-1(APEX) gene and the development of sporadic colorectal cancer. "
|5.||Xeroderma Pigmentosum (Kaposi's Disease)
01/01/2014 - "We conducted a case-control study to investigate the association of Human apurinic/apyrimidinic (AP) endonuclease (APEX1) Asp148Glu (rs1130409), Xeroderma Pigmentosum group D (XPD) Lys751Gln (rs13181), X-ray repair cross-complementing group 1 (XRCC) Arg399Gln (rs25487) and X-ray repair cross-complementing group 3 (XRCC3) Thr241Met (rs861539) polymorphisms with PE in a Mexican population. "
06/09/1995 - "A human apurinic/apyrimidinic endonuclease activity, called AP endonuclease I, is missing from or altered specifically in cells cultured from Xeroderma pigmentosum group-D individuals (XP-D cells) (Kuhnlein, U., Lee, B., Penhoet, E. "
03/01/1978 - "Xeroderma pigmentosum fibroblasts of the D group lack an apurinic DNA endonuclease species with a low apparent Km."
08/01/2014 - "We demonstrated that apurinic endonuclease (APE), X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), xeroderma pigmentosum D (XPD), and hOGG1 gene variants were associated with an increased risk for development of migraine disease (p<0.05). "
02/01/1978 - "We report here normal levels of apurinic endonuclease activity in extracts of cell lines derived from patients with ataxia telangiectasia, xeroderma pigmentosum (complementation group D), Cockayne dwarfism, Fanconi anemia and Bloom syndrome."
|1.||DNA Glycosylases (DNA Glycosylase)
|4.||A-Form DNA (A-DNA)
|5.||DNA (Deoxyribonucleic Acid)
|8.||RNA (Ribonucleic Acid)
|10.||Exonucleases (3' 5' Exonuclease)
|1.||Drug Therapy (Chemotherapy)