|1.||Wolf, Barry: 4 articles (09/2011 - 11/2002)|
|2.||Wolf, B: 3 articles (07/2014 - 01/2003)|
|3.||Coşkun, Turgay: 2 articles (08/2015 - 05/2004)|
|4.||Dursun, Ali: 2 articles (08/2015 - 05/2004)|
|5.||Ralhan, Ranju: 2 articles (01/2012 - 11/2010)|
|6.||Walfish, Paul G: 2 articles (01/2012 - 11/2010)|
|7.||So, Anthony K-C: 2 articles (01/2012 - 11/2010)|
|8.||Vurucu, Sebahattin: 2 articles (06/2009 - 09/2006)|
|9.||Unay, Bulent: 2 articles (06/2009 - 09/2006)|
|10.||Akin, Ridvan: 2 articles (06/2009 - 09/2006)|
09/01/2006 - "As a conclusion, the partial alopecia which is an initial symptom of reduced biotinidase activity may also be created depending on the reduction of biotinidase activity during valproic acid therapy. "
01/01/2009 - "Use of these powdered milks caused skin diseases and alopecia in some patients possessing thermolabile serum biotinidase, and administration of free biotin improved their symptoms dramatically. "
06/01/2009 - "The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid."
01/01/1999 - "Since biotinidase is mainly produced in the liver and partial biotinidase deficiency causes dermatological manifestations, seborrheic dermatitis, alopecia etc., isotretinoin side effects in relation to biotinidase activity were studied. "
09/01/2006 - "In this study we aimed to put forward the biotinidase deficiency considered as a possible cause of alopecia in the rats administered with valproic acid, and the correlation between liver and serum biotinidase enzyme activities (BEA) and transaminases, albumin and serum valproic acid levels. "
|4.||Atopic Dermatitis (Atopic Eczema)
|5.||Biotinidase Deficiency (Multiple Carboxylase Deficiency, Late Onset)
04/01/2001 - "This study characterises the spectrum of biotinidase mutations in 21 patients (17 families) with profound biotinidase deficiency (BD) and 13 unrelated patients with partial BD using a denaturing gradient gel electrophoretic mutation screening and selective sequencing approach. "
01/01/1990 - "Seventeen partially biotinidase-deficient patients detected by neonatal screening or family studies were compared with four patients with classical biotinidase deficiency. "
03/01/2015 - "To date, more than 100 mutations in the biotinidase gene known to cause biotinidase deficiency have been reported. "
09/01/2014 - "Multiple carboxylase deficiency (late onset) due to deficiency of biotinidase."
07/01/2014 - "Essentially all the mutations result in enzymatic activities with less than 10% of mean normal serum enzyme activity (profound biotinidase deficiency) with the exception of the c.1330G>C (p.D444H) mutation, which results in an enzyme having 50% of mean normal serum activity and causes partial biotinidase deficiency (10-30% of mean normal serum biotinidase activity) if there is a mutation for profound biotinidase deficiency on the second allele. "
|1.||Biotin (Vitamin H)
|2.||Late-onset multiple carboxylase deficiency
|3.||Valproic Acid (Valproate, Semisodium)
|10.||DNA (Deoxyribonucleic Acid)