A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 22.214.171.124) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.
Also Known As:
Monophosphatidylinositol Phosphodiesterase; 1 Phosphatidylinositol Phosphodiesterase; Diacylglycerol-Lyase, Phosphatidylinositol; Phosphatidylinositol Diacylglycerol Lyase; Phosphodiesterase, 1-Phosphatidylinositol; Phosphodiesterase, Monophosphatidylinositol; 1-Phosphatidylinositol Phosphodiesterase
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