|1.||Pihlajaniemi, Taina: 19 articles (08/2015 - 04/2002)|
|2.||Heljasvaara, Ritva: 15 articles (08/2015 - 10/2002)|
|3.||Sormunen, Raija: 6 articles (07/2014 - 12/2003)|
|4.||Salo, Tuula: 5 articles (08/2015 - 06/2003)|
|5.||Olsen, Bjorn R: 5 articles (05/2005 - 04/2002)|
|6.||Aikio, Mari: 4 articles (08/2015 - 11/2013)|
|7.||Alitalo, Kari: 4 articles (12/2007 - 10/2002)|
|8.||Schluesener, Hermann J: 4 articles (08/2007 - 12/2002)|
|9.||Rehn, Marko: 4 articles (01/2007 - 04/2003)|
|10.||Eklund, Lauri: 4 articles (09/2004 - 04/2002)|
01/01/2012 - "Other endogenous molecules carrying frizzled CRDs inhibit Wnt signaling, such as V3Nter, which is proteolytically derived from the cell surface component collagen XVIII and contains a biologically active frizzled domain (FZC18) inhibiting in vivo cell proliferation and tumor growth in mice. "
08/15/2004 - "A multivariate analysis with Cox proportional hazards model for disease-specific survival revealed that expression of collagen XVIII (strongly positive versus negative; weakly positive versus negative), tumor classification, and regional lymph node classification were independent prognostic factors. "
04/15/2004 - "The prevalence of positive collagen XVIII expression was greater in T2-4 tumors than in T1 tumors (P = 0.0235). "
04/15/2004 - "Low collagen XVIII expression levels were found in 75 tumor specimens, while high collagen XVIII expression levels were noted in 87 tumor specimens. "
04/15/2004 - "Collagen XVIII expression was detected in 162 of 221 patients with NSCLC (73%), primarily in the tumor cell cytoplasm. "
|2.||Diabetic Nephropathies (Diabetic Nephropathy)
02/01/2007 - "We previously reported the therapeutic efficacy of endostatin peptide, a potent inhibitor of angiogenesis derived from type XVIII collagen, in a mouse diabetic nephropathy model. "
10/01/2005 - "Here, we examine the effect of endostatin peptide, a potent inhibitor of angiogenesis derived from type XVIII collagen, in preventing progression in the type 1 diabetic nephropathy mouse model. "
06/01/2010 - "Further studies on larger patient populations are warranted to validate the utility of collagen XVIII as a prognostic biomarker in gastric carcinoma."
04/15/2004 - "To confirm the specificity of the collagen XVIII polyclonal antibody used in the current study and to test the expression of collagen XVIII in human lung carcinoma, Western blot analysis was performed on a panel of human lung carcinoma cell lines. "
04/15/2004 - "The purpose of the current study was to evaluate whether the expression of collagen XVIII has additional prognostic value for survival in patients with nonsmall cell lung carcinoma (NSCLC). "
06/01/2010 - "High expression of collagen XVIII is associated with poor prognosis in patients with metastatic gastric carcinoma. "
06/01/2010 - "The prognosis for patients with high collagen XVIII-expressing gastric carcinoma was significantly worse than that for patients displaying low or moderate collagen XVIII expression (median survival time, 7.8 months vs. 18.3 months [log-rank, p = 0.01]; median time to progression, 3 months vs. 8 months [log-rank, p = 0.01]). "
|4.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/01/2007 - "Using immunohistochemistry and in situ hybridization, we studied the expression and localization of collagen XVIII in different stages of normal oral wound healing, epithelial dysplasia and squamous cell carcinoma (SCC). "
07/01/2002 - "The present study sought to determine whether the oral squamous carcinoma cells expressed and produced collagen XVIII, a known precursor of endostatin. "
12/01/2003 - "Phenotypic switching of VEGF and collagen XVIII during hypoxia in head and neck squamous carcinoma cells."
03/20/2005 - "Endostatin inhibits nitric oxide and diminishes VEGF and collagen XVIII in squamous carcinoma cells."
|5.||Brain Injuries (Brain Injury)
01/01/2013 - "Recent studies have suggested that endogenous angiogenesis inhibitor endostatin/collagen XVIII might play an important role in the secondary brain injury following traumatic brain injury (TBI). "
01/01/2013 - "Endostatin/collagen XVIII is increased in cerebrospinal fluid after severe traumatic brain injury."
12/01/2007 - "Lesional expression of the endogenous angiogenesis inhibitor endostatin/collagen XVIII following traumatic brain injury (TBI)."
07/13/2007 - "Here we studied expression of endostatin/collagen XVIII in a rat traumatic brain injury (TBI) model, focusing on the early phase. "
07/01/2006 - "Endostatin/collagen XVIII accumulates in patients with traumatic brain injury."
|3.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|5.||Reactive Oxygen Species (Oxygen Radicals)
|10.||cobaltous chloride (cobalt(II)chloride)