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Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)

An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.
Also Known As:
Dihydropyrimidine Dehydrogenase; Dihydrothymine Dehydrogenase (NADP); Dehydrogenase, Dihydropyrimidine
Networked: 503 relevant articles (32 outcomes, 73 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Fukushima, Masakazu: 16 articles (08/2010 - 01/2002)
2. Fukushima, M: 13 articles (03/2012 - 01/2000)
3. Danenberg, Peter V: 9 articles (09/2010 - 02/2003)
4. Ichikawa, Wataru: 8 articles (07/2015 - 02/2002)
5. Diasio, Robert B: 8 articles (05/2014 - 11/2003)
6. Ishida, Hideyuki: 8 articles (11/2011 - 11/2002)
7. Ohsawa, Tomonori: 7 articles (11/2011 - 11/2002)
8. Danenberg, Kathleen D: 7 articles (12/2008 - 02/2003)
9. Brabender, Jan: 6 articles (03/2015 - 02/2003)
10. Sugihara, Kenichi: 6 articles (01/2015 - 07/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Breast Neoplasms (Breast Cancer)
4. Stomach Neoplasms (Stomach Cancer)
5. Adenocarcinoma

Related Drugs and Biologics

1. Fluorouracil (Carac)
2. Thymidylate Synthase
3. Thymidine Phosphorylase
4. capecitabine (Xeloda)
5. Enzymes
6. Orotate Phosphoribosyltransferase
7. Tegafur
8. Uracil
9. Messenger RNA (mRNA)
10. doxifluridine

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Adjuvant Chemotherapy
3. Radiotherapy
4. Heterologous Transplantation (Xenotransplantation)
5. Lasers (Laser)