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Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)

An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.
Also Known As:
Dihydropyrimidine Dehydrogenase; Dihydrothymine Dehydrogenase (NADP); Dehydrogenase, Dihydropyrimidine
Networked: 700 relevant articles (41 outcomes, 93 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Fukushima, Masakazu: 18 articles (01/2017 - 01/2002)
2. van Kuilenburg, André B P: 14 articles (01/2021 - 05/2002)
3. Fukushima, M: 13 articles (03/2012 - 01/2000)
4. Diasio, Robert B: 12 articles (05/2014 - 11/2003)
5. Ishida, Hideyuki: 9 articles (05/2012 - 11/2002)
6. Danenberg, Peter V: 9 articles (09/2010 - 02/2003)
7. Ichikawa, Wataru: 8 articles (07/2015 - 02/2002)
8. Ohsawa, Tomonori: 8 articles (05/2012 - 11/2002)
9. Saif, Muhammad Wasif: 8 articles (06/2010 - 09/2006)
10. Ciccolini, Joseph: 7 articles (01/2020 - 10/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Stomach Neoplasms (Stomach Cancer)
4. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Fluorouracil (Carac)
2. Thymidylate Synthase
3. Thymidine Phosphorylase
4. Enzymes
5. Capecitabine (Xeloda)
6. Tegafur
7. Orotate Phosphoribosyltransferase
8. Oxaliplatin (Eloxatin)
9. Uracil
10. doxifluridine

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Adjuvant Chemotherapy
3. Therapeutics
4. Radiotherapy
5. Chemoradiotherapy