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Positive Transcriptional Elongation Factor B

A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including TYPE T CYCLINS and cyclin K. It functions by phosphorylating the carboxy-terminal domain of RNA POLYMERASE II.
Also Known As:
P-TEFb; Positive Transcription Elongation Factor B; tat-Associated Kinase; tat Associated Kinase
Networked: 68 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Zhou, Qiang: 8 articles (01/2015 - 02/2004)
2. Shilatifard, Ali: 5 articles (09/2012 - 02/2010)
3. Lin, Chengqi: 5 articles (09/2012 - 02/2010)
4. Luo, Kunxin: 3 articles (01/2015 - 03/2008)
5. Siddiqui, M A Q: 3 articles (11/2012 - 07/2007)
6. Chaqour, Brahim: 3 articles (11/2012 - 07/2007)
7. Smith, Edwin R: 3 articles (12/2011 - 02/2010)
8. He, Nanhai: 3 articles (09/2011 - 03/2008)
9. Lu, Huasong: 2 articles (01/2015 - 01/2014)
10. Xue, Yuhua: 2 articles (01/2015 - 09/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Infection
3. Acquired Immunodeficiency Syndrome (AIDS)
4. Thymoma (Thymic Carcinoma)
5. Cardiomegaly (Heart Hypertrophy)

Related Drugs and Biologics

1. Positive Transcriptional Elongation Factor B
2. flavopiridol
3. Phosphotransferases (Kinase)
4. DNA (Deoxyribonucleic Acid)
5. Cyclins
6. Small Nuclear RNA (snRNA)
7. Peptide Elongation Factors (Elongation Factor)
8. Doxorubicin (Adriamycin)
9. Chromatin
10. Interleukin-8 (Interleukin 8)