|1.||Walker, Brian R: 7 articles (06/2010 - 11/2002)|
|2.||Stewart, P M: 7 articles (09/2004 - 08/2000)|
|3.||Seckl, Jonathan R: 6 articles (12/2011 - 04/2004)|
|4.||Chapman, Karen E: 4 articles (12/2011 - 01/2006)|
|5.||Stewart, Paul M: 4 articles (01/2010 - 08/2005)|
|6.||White, P C: 4 articles (12/2001 - 08/2000)|
|7.||Cherkasova, O P: 3 articles (03/2013 - 01/2006)|
|8.||Ohzeki, Takehiko: 3 articles (12/2011 - 05/2004)|
|9.||Nakagawa, Yuichi: 3 articles (12/2011 - 05/2004)|
|10.||Pácha, Jirí: 3 articles (09/2009 - 07/2004)|
|1.||Asthma (Bronchial Asthma)
04/01/2002 - "Clinical relevance of airway 11beta-hydroxysteroid dehydrogenase type II enzyme in asthma."
04/01/1994 - "A novel 11 beta-hydroxysteroid dehydrogenase inhibitor contained in saiboku-to, a herbal remedy for steroid-dependent bronchial asthma."
12/13/2004 - "Postmenopausal asthma: the estradiol 11beta-hydroxysteroid dehydrogenase connection."
11/01/2000 - "6. Although other studies have shown that high concentrations of magnolol inhibit acyl-CoA: cholesterol acyltransferase and 11 beta-hydroxysteroid dehydrogenase in a cell-free system, our data show that, in adrenal cell cultures, low concentrations of magnolol have a stimulatory effect on steroidogenesis, and the glucocorticoid produced may explain the effective control of asthma by Magnolia officinalis."
|2.||Hypertension (High Blood Pressure)
08/01/2008 - "Epigenetic control of 11 beta-hydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension."
11/01/2006 - "[The activity of 11beta-hydroxysteroid dehydrogenase of rat kidney and liver at inherited stress-induced arterial hypertension]."
08/15/2006 - "Enhanced 11beta-hydroxysteroid dehydrogenase activity, the metabolic syndrome, and systemic hypertension."
01/01/2006 - "11beta-Hydroxysteroid dehydrogenase activity in the kidneys of NISAG rats (rat strain with hereditary stress-induced arterial hypertension) was 1.5-fold higher than in WAG rats. "
08/01/2005 - "The HSD11B2 gene, encoding the kidney isoenzyme 11beta-hydroxysteroid dehydrogenase, is a candidate for essential hypertension. "
06/17/2000 - "To study 11 beta-hydroxysteroid dehydrogenase activity in Cushing's syndrome. "
06/17/2000 - "11 beta-hydroxysteroid dehydrogenase activity is decreased in patients with Cushing's syndrome."
01/01/1999 - "Relative 11beta-hydroxysteroid dehydrogenase deficiency has been shown previously to arise from endogenous hypercortisolism in diseases of the hypothalamic/pituitary/adrenocortical system; whether stress induced hypercortisolism may also result in substrate overload of 11beta-hydroxysteroid dehydrogenase has not yet been studied. "
12/01/1995 - "11 beta-Hydroxysteroid dehydrogenase activity in Cushing's syndrome: explaining the mineralocorticoid excess state of the ectopic adrenocorticotropin syndrome."
08/01/2008 - "A case of cortisol producing adrenal adenoma without phenotype of Cushing's syndrome due to impaired 11beta-hydroxysteroid dehydrogenase 1 activity."
|4.||Breast Neoplasms (Breast Cancer)
04/01/2000 - "This study examined the enzymatic characteristics and steroid regulation of the glucocorticoid-metabolizing enzyme 11beta-hydroxysteroid dehydrogenase (11beta-HSD) in the human breast cancer cell line T-47D. "
01/01/2001 - "Expression of the 11beta-hydroxysteroid dehydrogenase type II enzyme in breast tumors and modulation of activity and cell growth in PMC42 cells."
04/01/2000 - "Progestin regulation of 11beta-hydroxysteroid dehydrogenase expression in T-47D human breast cancer cells."
10/01/1997 - "Inhibition of 11 beta-hydroxysteroid dehydrogenase activity enhances the antiproliferative effect of glucocorticosteroids on MCF-7 and ZR-75-1 breast cancer cells."
10/01/1997 - "This in vitro study on MCF-7 and ZR-75-1 breast cancer cells showed that the antiproliferative action of glucocorticosteroids (GCS) on breast cancer cells is weakened by a high oxidative activity of 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD; EC 22.214.171.124): both endogenic as well as synthetic GCS (dexamethasone, prednisolone) were metabolised to hormonally inactive 11-dehydro metabolites. "
01/01/2006 - "In the past years the interaction of GH and 11beta hydroxysteroid dehydrogenase (11betaHSD) in the pathogenesis of central obesity has been suggested. "
04/01/2004 - "Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice."
11/01/2003 - "The transgenic mouse overexpressing 11beta-hydroxysteroid dehydrogenase (11beta-HSD) develops visceral obesity. "
02/01/2001 - "Lack of mutations of type 1 11beta-hydroxysteroid dehydrogenase gene in patients with abdominal obesity."
11/01/2000 - "The role of 11 beta-hydroxysteroid dehydrogenase in central obesity and osteoporosis."
|4.||Messenger RNA (mRNA)
|6.||Mineralocorticoid Receptors (Mineralocorticoid Receptor)
|8.||Glucocorticoid Receptors (Glucocorticoid Receptor)
|9.||Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)
|2.||Renal Dialysis (Hemodialysis)
|3.||Gastric Bypass (Roux-en-Y Gastric Bypass)