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Angiopoietin-2

An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.
Also Known As:
Angiopoietin 2
Networked: 645 relevant articles (7 outcomes, 70 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. David, Sascha: 16 articles (07/2015 - 01/2008)
2. Kümpers, Philipp: 16 articles (03/2013 - 01/2008)
3. Haller, Hermann: 14 articles (07/2015 - 01/2008)
4. Kielstein, Jan T: 11 articles (07/2015 - 01/2008)
5. Lukasz, Alexander: 11 articles (01/2014 - 01/2008)
6. Liles, W Conrad: 10 articles (01/2015 - 01/2011)
7. De Palma, Michele: 8 articles (02/2015 - 06/2007)
8. Bhandari, Vineet: 8 articles (01/2014 - 05/2007)
9. Reiss, Yvonne: 7 articles (07/2015 - 02/2006)
10. Giamarellos-Bourboulis, Evangelos J: 7 articles (01/2014 - 11/2008)

Related Diseases

1. Neoplasms (Cancer)
2. Inflammation
3. Sepsis (Septicemia)
4. Macular Degeneration (Age-Related Maculopathy)
5. Systemic Scleroderma (Systemic Sclerosis)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. glucuronyl glucosamine glycan sulfate (Vessel)
3. Cyclophosphamide (Cytoxan)
4. Angiopoietin-1
5. Messenger RNA (mRNA)
6. TIE-2 Receptor (Receptor, TIE 2)
7. Biological Markers (Surrogate Marker)
8. Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)
9. angiogenin
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Transplants (Transplant)
3. Drug Therapy (Chemotherapy)
4. Vitrectomy
5. Homologous Transplantation (Allograft)