Endocrine-Gland-Derived Vascular Endothelial Growth Factor (Vascular Endothelial Growth Factor, Endocrine Gland Derived)

A vascular endothelial growth factor whose expression is found largely restricted to the GONADS; ADRENAL CORTEX; and PLACENTA. It has similar biological activity to VASCULAR ENDOTHELIAL GROWTH FACTOR-A.

Also Known As:

Networked: 68 relevant articles (1 outcomes, 22 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Alfaidy, Nadia: 10 articles (03/2021 - 04/2006)
2.	Benharouga, Mohamed: 8 articles (03/2021 - 01/2014)
3.	Feige, Jean-Jacques: 7 articles (01/2016 - 04/2006)
4.	Goi, Takanori: 6 articles (10/2021 - 03/2004)
5.	Hoffmann, Pascale: 6 articles (03/2021 - 04/2006)
6.	Brouillet, Sophie: 6 articles (01/2020 - 10/2012)
7.	Traboulsi, Wael: 5 articles (03/2021 - 08/2015)
8.	Yamaguchi, Akio: 5 articles (05/2015 - 03/2004)
9.	Aboussaouira, Touria: 4 articles (01/2020 - 01/2014)
10.	Cîmpean, Anca Maria: 4 articles (03/2019 - 01/2012)

Related Diseases

1.	Pituitary Neoplasms (Pituitary Adenoma) 10/01/2010 - "In this study, we investigated by immunohistochemistry the expression of EG-VEGF in 2 samples of normal adenohypophysis and 43 bioptic samples of pituitary adenoma. " 10/01/2010 - "On the basis of our data showing a marked decrease in the expression of EG-VEGF in pituitary adenoma, with the exception of LH-secreting adenomas, we suggest that LH might be involved in the induction of EG-VEGF secretion." 03/05/2019 - "We aim to study VEGF, VEGF165b and EG-VEGF expression in pituitary adenomas. " 10/01/2010 - "The results of this study for the first time demonstrate a down-regulation of EG-VEGF expression in human pituitary adenoma as compared to normal adenohypophysis, suggesting an impaired function of the neoplastic cells in terms of hormone release in the blood stream, as a consequence of impaired tumor angiogenesis in the tumor. " 03/05/2019 - "Our data strongly support VEGF, VEGF165b and EG-VEGF as important players of pituitary adenomas tumorigenesis. "
2.	Adenoma (Adenomas) 10/01/2010 - "On the basis of our data showing a marked decrease in the expression of EG-VEGF in pituitary adenoma, with the exception of LH-secreting adenomas, we suggest that LH might be involved in the induction of EG-VEGF secretion." 12/01/2015 - "The mean EG-VEGF mRNA expression was significantly lower in ACC (606.5 ± 77.1 copies) compared to NAG (4,043 ± 1,111) and cortisol-producing adenomas (CPA) (4,433 ± 2,378) (p < 0.01 and p < 0.05, respectively). "
3.	Neoplasms (Cancer) 02/06/2018 - "Altogether these findings suggest that EG-VEGF/receptors system might be an important actor in the CRC progression into PC and might be involved in the ability of tumor cells to invade other organs. " 02/06/2018 - "Furthermore, according to clinicopathologic examinations, local EG-VEGF expression correlated with higher tumor and nodal stages (p< 0.001) of CRC. " 11/15/2017 - "Treatment of the animal model with EG-VEGF receptor's antagonists significantly reduced tumor development and progression and preserved pregnancy. " 01/01/2017 - "Thus, our present paper has been focused on the role of EG-VEGF in normal tissues and various malignant tumors and their angiogenic processes." 12/01/2015 - "These findings suggest that EG-VEGF and its receptor PKR1 might play a role in the pathogenesis of adrenocortical tumors and could serve as prognostic markers for this rare malignant disease."
4.	Colorectal Neoplasms (Colorectal Cancer) 12/01/2007 - "In this study, we investigated the expression of EG-VEGF in colorectal cancer, the relationship between its expression and clinicopathological factors, and the in vitro activity of EG-VEGF transfectants. " 12/01/2007 - "We speculate that, in colorectal cancers, the EG-VEGF gene functions as an important factor in angiogenesis in primary and metastatic lesions, and consider that it is useful as a novel prognostic factor. " 12/01/2007 - "We determined expression levels of EG-VEGF in 113 advanced colorectal cancers resected in our hospital by quantitative PCR, and compared the expression levels and clinicopathological findings by multivariate analyses. " 03/15/2004 - "The expression of EG-VEGF was confirmed in all of the colorectal cancer cell lines. " 03/15/2004 - "We evaluated the involvement of EG-VEGF in colorectal cancer. "
5.	Hepatocellular Carcinoma (Hepatoma) 02/28/2008 - "To study the implication of prokineticin 1 (PK1/EG-VEGF) and prokineticin 2 (PK2/Bv8) in hepatocellular carcinoma angiogenesis. " 09/01/2006 - "The aim of the present study was to detect the correlation between the expression of vascular endothelial growth factor (VEGF), angiopoietin 2 (Ang2), ephrinB2 and endocrine gland-derived vascular endothelial growth factor (EG-VEGF) and carcinogenesis or portal vein tumor thrombus (PVTT) formation in human hepatocellular carcinoma (HCC). "

Related Drugs and Biologics

1.	Endocrine-Gland-Derived Vascular Endothelial Growth Factor (Vascular Endothelial Growth Factor, Endocrine Gland Derived)
2.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
3.	Proteins (Proteins, Gene)
4.	Angiopoietin-2
5.	Messenger RNA (mRNA)
6.	Angiogenesis Inducing Agents (Angiogenesis Factor)
7.	Hormones (Hormone)
8.	Progesterone Receptors (Progesterone Receptor)
9.	Testosterone (Sustanon)
10.	Estrogen Receptors

Related Therapies and Procedures

1.	Moxibustion
2.	Therapeutics
3.	Lasers (Laser)
4.	Drug Therapy (Chemotherapy)
5.	Analgesia