Acute Traumatic Stress Disorders (Acute Stress Disorder)

A class of traumatic stress disorders that is characterized by the significant dissociative states seen immediately after overwhelming trauma. By definition it cannot last longer than 1 month, if it persists, a diagnosis of post-traumatic stress disorder (STRESS DISORDERS, POST-TRAUMATIC) is more appropriate.

Also Known As:

Networked: 90 relevant articles (2 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
2.	Wounds and Injuries (Trauma)
3.	Burns
4.	Postpartum Depression (Post-Natal Depression)
5.	Anxiety Disorders (Anxiety Disorder)

Experts

1.	Nixon, Reginald D V: 6 articles (12/2012 - 10/2003)
2.	Bryant, Richard A: 5 articles (02/2007 - 10/2003)
3.	Bisson, Jonathan I: 4 articles (01/2021 - 11/2005)
4.	Schnyder, Ulrich: 4 articles (01/2021 - 01/2010)
5.	Moulds, Michelle L: 4 articles (09/2006 - 10/2003)
6.	Barth, Jürgen: 3 articles (01/2021 - 01/2017)
7.	Meister-Langraf, Rebecca E: 3 articles (01/2021 - 01/2017)
8.	Princip, Mary: 3 articles (01/2021 - 01/2017)
9.	Schmid, Jean-Paul: 3 articles (01/2021 - 01/2017)
10.	Znoj, Hansjörg: 3 articles (01/2021 - 01/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Acute Traumatic Stress Disorders:

1.	Imipramine (Janimine)FDA LinkGeneric 10/01/2010 - "Two brief, small, double-blind, randomized controlled trials of imipramine for children and adolescents with acute stress disorder have been conducted, with mixed results. " 07/01/1999 - "Imipramine treatment in pediatric burn patients with symptoms of acute stress disorder: a pilot study." 11/01/2005 - "Early treatment of acute stress disorder with either imipramine or fluoxetine is often able to reduce its symptoms. " 07/01/2010 - "Three double-blind, randomized controlled trials of selective serotonin reuptake inhibitors (SSRIs) and 1 double-blind randomized controlled trial of imipramine in children and adolescents with PTSD or acute stress disorder were identified. " 11/01/2005 - "This study examines retrospectively the response rate of pediatric burn survivors with acute stress disorder to either imipramine or fluoxetine. "
2.	KetamineFDA LinkGeneric 11/27/2023 - "Intravenous Ketamine Exacerbating Symptoms of Acute Stress Disorder: A Case Report and Systematized Review of Existing Literature." 09/01/2012 - "[Ketamine and symptoms of acute stress disorder]." 07/01/2008 - "Ketamine aggravates symptoms of acute stress disorder in a naturalistic sample of accident victims." 07/01/2008 - "The aim of the present study was to examine whether ketamine administration after moderate accidental trauma modulates dissociation and other symptoms of acute stress disorder (ASD) in the direct aftermath of the event. "
3.	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/01/2019 - "To assess the association between brain-derived neurotrophic factor (BDNF) levels and acute stress disorder (ASD) in patients who have suffered physical trauma. " 03/01/2009 - "The aim of this study was to evaluate brain-derived neurotrophic factor levels in two patients, one with posttraumatic stress disorder and one with acute stress disorder, before and after treatment, and to compare those levels to those of healthy controls. " 03/01/2009 - "These results suggest that serum levels of brain-derived neurotrophic factor, as opposed to what has been described in mood disorders, are increased in posttraumatic stress disorder as well as in acute stress disorder."
4.	Tuberculin (PPD)IBA 09/01/2010 - "The purpose of this study was to assess the prevalence and correlates of acute stress disorder (ASD) and posttraumatic stress disorder (PTSD) in mothers and fathers, and postpartum depression (PPD) in mothers, of infants in the Neonatal Intensive Care Unit (NICU). " 09/01/2022 - "Obstetric violence may have a profound psychological impact: post-partum acute stress disorder (ASD), post-traumatic stress disorder (PTSD), and post-partum depression (PPD) are all well-documented mental health consequences of maternal mistreatment. "
5.	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 12/01/2012 - "The study tested the efficacy and tolerability of cognitive processing therapy (CPT) for survivors of assault with acute stress disorder. " 01/01/2005 - "This case study describes Cognitive Processing Therapy (CPT) with a 30-year-old gay man with symptoms of acute stress disorder (ASD) following a recent homophobic assault. "
6.	RiluzoleFDA LinkGeneric 01/01/2023 - "This review included: (1) studies involving participants that were patients with generalized anxiety disorder (GAD), social anxiety disorder, panic disorder, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), acute stress disorder, or phobias; and (2) randomized controlled trials (RCTs) or intervention studies (e.g., single arm trials) examining the effects and safety of riluzole. "
7.	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 07/01/2010 - "Three double-blind, randomized controlled trials of selective serotonin reuptake inhibitors (SSRIs) and 1 double-blind randomized controlled trial of imipramine in children and adolescents with PTSD or acute stress disorder were identified. "
8.	Fluoxetine (Prozac)FDA LinkGeneric 11/01/2005 - "Early treatment of acute stress disorder with either imipramine or fluoxetine is often able to reduce its symptoms. " 11/01/2005 - "This study examines retrospectively the response rate of pediatric burn survivors with acute stress disorder to either imipramine or fluoxetine. " 11/01/2005 - "On retrospective chart review, 128 intensive care unit patients (85 boys, 43 girls) with 52%+/- 20% total body surface area burn, length of stay of 32.8+/- 25.2 days, mean age of 9.1+/- 4.7 yrs, and age range of 13 months to 19 yrs met criteria for acute stress disorder after >or=2 days of symptoms and were treated with either imipramine or fluoxetine. "
9.	Aligeron (AS 2)IBA 09/01/2010 - "Studies have shown that greater levels of acute pain are associated with negative long-term psychological effects such as acute stress disorder, depression, suicidal ideation, and post-traumatic stress disorder for as long as 2 years after the initial burn injury. "
10.	Hypnotics and Sedatives (Sedatives)IBA 10/01/2003 - "Acutely traumatized participants with acute stress disorder (N = 45) were administered the Stanford Hypnotic Clinical Scale (SHCS) within 4 weeks of their trauma. " 04/01/2001 - "Acutely traumatized patients (N=61) with acute stress disorder, subclinical acute stress disorder (no dissociative symptoms), and no acute stress disorder were administered the Stanford Hypnotic Clinical Scale within 4 weeks of their trauma. " 09/01/2002 - "White noise may be a simple, safe, cost-effective alternative to hypnotic medication in many psychiatric disorders, especially acute stress disorder and PTSD." 11/01/2007 - "Pharmacological treatment of acute stress disorder with propranolol and hypnotics."

Therapies and Procedures

1.	Therapeutics 12/01/2012 - "Cognitive processing therapy versus supportive counseling for acute stress disorder following assault: a randomized pilot trial." 07/18/2007 - "The first trial (n = 24) showed a benefit of cognitive behavioural therapy (CBT) in people with mild TBI and acute stress disorder. " 10/01/2020 - "Attention control therapy for acute stress disorder: A randomized controlled trial." 05/01/2015 - "In the current case study, telehealth technology was used to support the delivery of PE therapy to treat a service member diagnosed with acute stress disorder in a war zone. " 01/01/2015 - "A model that suggests reconsolidation of traumatic memories as a mechanism of change in therapy is important, but problematic to generalize to disorders other than post-traumatic and acute-stress disorder. "
2.	Drug Therapy (Chemotherapy) 03/01/2002 - "PsycLIT, PsychINFO, PILOTS, and MEDLINE databases were searched from January 1985 to December 2000 using the terms "acute stress disorder," "posttraumatic stress disorder," "traumatic stress," "psychotherapy," "psychosocial treatment," "treatment," and "pharmacotherapy." Recommendations concerning treatment of acute stress disorder (ASD) and posttraumatic stress disorder (PTSD) are based on evidence from trials of the highest quality. " 12/09/2019 - "A systematic search was undertaken to identify RCTs, which used early pharmacotherapy (within three months of a traumatic event) to prevent and treat PTSD and acute stress disorder (ASD) in children and adults. " 01/01/2006 - "Treatment of PTSD in association with other comorbid conditions is addressed, and the role of pharmacotherapy in treating early PTSD and acute stress disorder is examined. " 10/01/2020 - "Evaluation of pharmacotherapies for acute stress disorder (ASD) or post-traumatic stress disorder (PTSD) is challenging due to robust heterogeneity of trauma histories and limited efficacy of any single candidate to reduce all stress-induced effects. " 03/01/2003 - "Current pharmacotherapy to ameliorate psychosocial problems associated with burns such as acute stress disorder, depression and post traumatic stress disorder are discussed. "
3.	Hypnosis (Mesmerism) 04/01/2005 - "This research represents the first controlled treatment study of hypnosis and cognitive- behavioral therapy (CBT) of acute stress disorder (ASD). " 09/01/2006 - "Hypnotherapy and cognitive behaviour therapy of acute stress disorder: a 3-year follow-up." 04/01/2005 - "The additive benefit of hypnosis and cognitive-behavioral therapy in treating acute stress disorder." 11/01/2005 - "Adding hypnosis to cognitive behavioural therapy may reduce some acute stress disorder symptoms." 10/01/2005 - "Three of these papers are original clinical research studies evaluating whether hypnosis can be useful in treating acute stress disorder, allergic rhinitis, and distress associated with an invasive medical procedure for children. "
4.	Aftercare (After-Treatment) 09/01/2006 - "The long-term benefits of cognitive behaviour therapy (CBT) for trauma survivors with acute stress disorder were investigated by assessing patients 3 years after treatment. " 03/01/2009 - "The aim of this study was to evaluate brain-derived neurotrophic factor levels in two patients, one with posttraumatic stress disorder and one with acute stress disorder, before and after treatment, and to compare those levels to those of healthy controls. "
5.	Critical Care (Surgical Intensive Care) 01/01/2022 - "Factors associated with critical care nurses' acute stress disorder after patient death." 12/01/2017 - "To determine if current levels of anxiety, depression and acute stress disorder symptoms differ significantly among family members of intensive-care-unit patients depending upon previous intensive-care experience. " 05/01/2005 - "Family representatives of 40 patients were administered a brief version of the Critical Care Family Needs Inventory, the Acute Stress Disorder Scale, the Brief Symptom Inventory, the Impact Message Inventory, and the Life Orientation Test shortly after admission of the patients to the intensive care unit and after discharge. " 06/20/2020 - "The review showed that during the admission and intensive care stage, pediatric medical traumatic stress and acute stress disorder were common, and it was recommended to focus on prevention and monitoring, including providing medical-related information for pediatric burn patients and their parents, encouraging parents to accompany pediatric burn patients, and screening these acute stress disorders in time. "