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Calgranulin B

A 13.2-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN A and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin B is expressed at high concentrations in GRANULOCYTES during early monocyte differentiation, and serum calgranulin B levels are elevated in many inflammatory disorders such as CYSTIC FIBROSIS.
Also Known As:
60B8-A Antigen; Antigen 60B8-A; CABP-P14; Leukocyte L1 Protein Heavy Chain; MRP-14 Protein; MRP14 Protein; Macrophage-Related Protein-14; Myeloid Calcium-Binding Protein p14; S100A9 Protein; 60B8 A Antigen; Antigen 60B8 A; Antigen, 60B8-A; MRP 14 Protein; Macrophage Related Protein 14; Myeloid Calcium Binding Protein p14
Networked: 58 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Yoo, Byong Chul: 2 articles (01/2014 - 11/2008)
2. Shen, Qi: 2 articles (07/2013 - 07/2012)
3. Jiang, Wenxiao: 2 articles (07/2013 - 07/2012)
4. Zhu, Xueqiong: 2 articles (07/2013 - 07/2012)
5. Vogl, Thomas: 2 articles (01/2010 - 09/2008)
6. Zreiqat, Hala: 2 articles (01/2010 - 12/2005)
7. Roth, Johannes: 2 articles (01/2010 - 09/2008)
8. Juliano, Maria Aparecida: 2 articles (10/2008 - 11/2006)
9. Giorgi, Renata: 2 articles (10/2008 - 11/2006)
10. Juliano, Luiz: 2 articles (10/2008 - 11/2006)

Related Diseases

1. Neoplasms (Cancer)
2. Interstitial Lung Diseases (Interstitial Lung Disease)
3. Idiopathic Pulmonary Fibrosis
4. Sarcoidosis (Schaumann Disease)
5. Chorioamnionitis
12/01/2009 - "(1) Among patients with histologic chorioamnionitis, the mRNA expression of alpha-defensin-1 and calgranulin B in the fetal membranes of patients with PTL and intact membranes as well as that of calgranulin B in the fetal membranes of patients with PPROM is higher than in the membranes of those without histologic chorioamnionitis; (2) histologic chorioamnionitis is associated with differences in the pattern of alpha-defensin-1 mRNA expression in the fetal membranes in patients with PTL and intact membranes and those with PPROM."
12/01/2009 - "(1) The expression of alpha-defensin-1 mRNA in the fetal membranes was higher in patients with PTL and intact membranes with histologic chorioamnionitis, than those without chorioamnionitis (19.4-fold, p < 0.001); (2) Among patients with histologic chorioamnionitis, patients with PTL and intact membranes had a higher alpha-defensin-1 mRNA expression than those with PPROM (5.5-fold, p = 0.003); (3) Histologic chorioamnionitis was associated with a higher calgranulin B mRNA expression in the chorioamniotic membranes of patients with both PTL and intact membranes (7.9-fold, p = 0.03) and PPROM (7.6-fold, p < 0.0001); (4) The expression of calgranulin B mRNA in the fetal membranes was higher in patients with PTL and intact membranes without histologic chorioamnionitis than in those with PPROM without histologic chorioamnionitis (2.7-fold, p = 0.03); (5) There were no differences in the expression of beta-defensin-1 and granulysin in the chorioamniotic membranes between the study groups even in the presence of histologic chorioamnioniotis. "

Related Drugs and Biologics

1. Messenger RNA (mRNA)
2. human DEFB1 protein
3. Calgranulin A
4. Proteins (Proteins, Gene)
5. Biological Markers (Surrogate Marker)
6. Carrier Proteins (Binding Protein)
7. Calcium
8. Calgranulin B
9. S100 Proteins (S 100 Protein)
10. Peroxidase (Myeloperoxidase)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)