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Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)

A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Also Known As:
fms-Like Tyrosine Kinase; Vascular Endothelial Growth Factor Receptor 1; FLT1 RTK; FLT1 Receptor Tyrosine Kinase; Proto-Oncogene Protein flt; VEGF Receptor flt-1 Protein; VEGF Receptor, FLT; FLT VEGF Receptor; Proto Oncogene Protein flt; Receptor, FLT VEGF; Tyrosine Kinase, fms-Like; VEGF Receptor flt 1 Protein; VEGFR-1
Networked: 785 relevant articles (15 outcomes, 106 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Karumanchi, S Ananth: 41 articles (11/2015 - 03/2003)
2. Shibuya, Masabumi: 17 articles (01/2015 - 10/2002)
3. Romero, Roberto: 15 articles (01/2015 - 06/2004)
4. Rana, Sarosh: 12 articles (11/2015 - 02/2007)
5. Chaiworapongsa, Tinnakorn: 12 articles (01/2015 - 06/2004)
6. Wu, Yan: 12 articles (02/2011 - 11/2004)
7. Thadhani, Ravi: 11 articles (11/2015 - 02/2004)
8. Levine, Richard J: 11 articles (04/2009 - 02/2004)
9. Kusanovic, Juan Pedro: 10 articles (04/2013 - 10/2006)
10. Rajakumar, Augustine: 9 articles (10/2014 - 12/2004)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Neoplasm Metastasis (Metastasis)
4. Inflammation
5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4. Antigens
5. IMC-18F1
6. Cytotoxins
7. Interleukin-6 (Interleukin 6)
8. Brain Natriuretic Peptide (Natrecor)
9. Thymidine Kinase
10. pro-brain natriuretic peptide (1-76)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Sutures (Suture)
3. Resuscitation
4. Heterologous Transplantation (Xenotransplantation)
5. Prostatectomy (Retropubic Prostatectomy)