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Vascular Endothelial Growth Factor Receptors (VEGF Receptors)

A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.
Also Known As:
VEGF Receptors; Vascular Endothelial Growth Factor Receptor; Receptors, Vascular Endothelial Growth Factor; Endothelial Growth Factor Receptor; Receptor, Endothelial Growth Factors; Receptor, Vascular Endothelial Cell Growth Factor; Receptor, Vascular Permeability Factor; VEGF Receptor; VPF Receptor; Vascular Endothelial Cell Growth Factor Receptor; Vascular Permeability Factor Receptor; Receptors, VEGF
Networked: 3385 relevant articles (175 outcomes, 491 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Voelkel, Norbert F: 22 articles (01/2020 - 05/2002)
2. Rini, Brian I: 21 articles (10/2022 - 01/2006)
3. Jain, Rakesh K: 21 articles (11/2020 - 01/2006)
4. Escudier, Bernard: 21 articles (08/2020 - 08/2005)
5. Hicklin, Daniel J: 18 articles (09/2008 - 04/2002)
6. Choueiri, Toni K: 17 articles (10/2022 - 10/2009)
7. Kim, Sinil: 17 articles (08/2015 - 11/2007)
8. Motzer, Robert J: 16 articles (10/2022 - 01/2006)
9. Duda, Dan G: 16 articles (11/2020 - 08/2002)
10. Atkins, Michael B: 15 articles (10/2022 - 01/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Renal Cell Carcinoma (Grawitz Tumor)
3. Colorectal Neoplasms (Colorectal Cancer)
4. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
5. Glioblastoma (Glioblastoma Multiforme)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. Tyrosine Kinase Inhibitors
3. Axitinib (AG 013736)
4. Sunitinib (Sutent)
5. cediranib (AZD2171)
6. Phosphotransferases (Kinase)
7. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)
8. ErbB Receptors (EGF Receptor)
9. Sorafenib (BAY 43-9006)
10. Bevacizumab (Avastin)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Radiotherapy
4. Immunotherapy
5. Microbubbles