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Neuropilin-2

Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.
Also Known As:
NRP2 Protein; Npn-2 Protein; Neuropilin 2; Npn 2 Protein
Networked: 147 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Datta, Kaustubh: 9 articles (01/2022 - 01/2016)
2. Muders, Michael H: 8 articles (01/2022 - 01/2016)
3. Dutta, Samikshan: 6 articles (01/2022 - 01/2016)
4. Klagsbrun, Michael: 6 articles (11/2016 - 11/2004)
5. Batra, Surinder K: 5 articles (01/2022 - 01/2016)
6. Roy, Sohini: 5 articles (01/2022 - 01/2016)
7. Bielenberg, Diane R: 5 articles (01/2017 - 11/2004)
8. Mayr, Thomas: 4 articles (01/2022 - 01/2019)
9. Shimizu, Akio: 4 articles (05/2011 - 11/2004)
10. Baretton, Gustavo B: 3 articles (01/2022 - 03/2016)

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Neoplasm Metastasis (Metastasis)
3. Neoplasms (Cancer)
4. Thyroid Neoplasms (Thyroid Cancer)
5. Colorectal Neoplasms (Colorectal Cancer)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Neuropilin-1
3. Semaphorins (Semaphorin)
4. Cell Surface Receptors
5. Long Noncoding RNA
6. Intercellular Signaling Peptides and Proteins (Growth Factors)
7. Chromogranin A
8. Nucleosomes (Nucleosome)
9. Hormones (Hormone)
10. Complement C2 (Complement Component 2)

Related Therapies and Procedures

1. Therapeutics
2. Chemoradiotherapy
3. Transplantation
4. Pneumonectomy (Lung Volume Reduction)
5. Drug Therapy (Chemotherapy)