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Neuropilin-2

Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.
Also Known As:
NRP2 Protein; Npn-2 Protein; Neuropilin 2; Npn 2 Protein
Networked: 69 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Klagsbrun, Michael: 5 articles (05/2011 - 11/2004)
2. Shimizu, Akio: 4 articles (05/2011 - 11/2004)
3. Roche, Joëlle: 3 articles (12/2013 - 07/2003)
4. Bielenberg, Diane R: 3 articles (10/2011 - 11/2004)
5. Bagri, Anil: 3 articles (01/2011 - 04/2008)
6. Liu, Ping: 2 articles (02/2016 - 01/2010)
7. Zhou, Qi: 2 articles (03/2015 - 01/2009)
8. Sun, Hong: 2 articles (04/2014 - 12/2012)
9. Liu, Yun: 2 articles (04/2014 - 12/2012)
10. Nasarre, Patrick: 2 articles (12/2013 - 02/2005)

Related Diseases

1. Neoplasm Metastasis (Metastasis)
2. Melanoma (Melanoma, Malignant)
3. Neoplasms (Cancer)
4. Thyroid Neoplasms (Thyroid Cancer)
5. Seizures (Seizure)

Related Drugs and Biologics

1. Chromogranin A
2. Nucleosomes (Nucleosome)
3. Hormones
4. Factor IX (PTC)
5. Antigens
6. papillary Thyroid cancer
7. Neuropilin-1
8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
9. Vascular Endothelial Growth Factor C
10. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Transplantation (Transplant Recipients)
3. Pneumonectomy (Lung Volume Reduction)
4. Drug Therapy (Chemotherapy)