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Neuropilin-1

A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
Also Known As:
A5 Antigen; NRP1 Protein; Npn-1 Protein; Sema III Receptor; Semaphorin III Receptor; Antigen, A5; Neuropilin 1; Npn 1 Protein; Receptor, Sema III
Networked: 707 relevant articles (10 outcomes, 64 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Mukhopadhyay, Debabrata: 12 articles (01/2022 - 12/2003)
2. Barberi-Heyob, Muriel: 11 articles (11/2021 - 05/2007)
3. Teesalu, Tambet: 10 articles (01/2022 - 12/2009)
4. Frochot, Céline: 9 articles (11/2021 - 05/2007)
5. Yan, Jianghua: 9 articles (01/2019 - 04/2013)
6. Lu, Weiyue: 9 articles (09/2018 - 10/2013)
7. Carmeliet, Peter: 7 articles (01/2022 - 02/2005)
8. Tamagnone, Luca: 7 articles (07/2021 - 04/2011)
9. Xie, Cao: 7 articles (09/2018 - 10/2013)
10. Zhang, Hua: 6 articles (01/2021 - 03/2014)

Related Diseases

1. Neoplasms (Cancer)
2. COVID-19
3. Breast Neoplasms (Breast Cancer)
4. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
5. Insulin Resistance

Related Drugs and Biologics

1. Peptides (Polypeptides)
2. Integrins
3. Messenger RNA (mRNA)
4. Biomarkers (Surrogate Marker)
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6. Tuftsin
7. Dendrimers (Dendrons)
8. Calreticulin
9. Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
10. arginyl-glycyl-aspartic acid

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
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4. Prostatectomy (Retropubic Prostatectomy)
5. Castration