Neuropilin-1
A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
Also Known As:
A5 Antigen; NRP1 Protein; Npn-1 Protein; Sema III Receptor; Semaphorin III Receptor; Antigen, A5; Neuropilin 1; Npn 1 Protein; Receptor, Sema III
Networked: 707
relevant articles (10 outcomes,
64 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Mukhopadhyay, Debabrata:
12 articles
(01/2022 - 12/2003)
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2. | Barberi-Heyob, Muriel:
11 articles
(11/2021 - 05/2007)
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3. | Teesalu, Tambet:
10 articles
(01/2022 - 12/2009)
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4. | Frochot, Céline:
9 articles
(11/2021 - 05/2007)
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5. | Yan, Jianghua:
9 articles
(01/2019 - 04/2013)
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6. | Lu, Weiyue:
9 articles
(09/2018 - 10/2013)
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7. | Carmeliet, Peter:
7 articles
(01/2022 - 02/2005)
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8. | Tamagnone, Luca:
7 articles
(07/2021 - 04/2011)
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9. | Xie, Cao:
7 articles
(09/2018 - 10/2013)
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10. | Zhang, Hua:
6 articles
(01/2021 - 03/2014)
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