|1.||Altevogt, Peter: 34 articles (03/2015 - 07/2003)|
|2.||Schachner, Melitta: 18 articles (06/2015 - 09/2002)|
|3.||Schirmer, Uwe: 11 articles (11/2014 - 01/2010)|
|4.||Moldenhauer, Gerhard: 10 articles (03/2015 - 01/2006)|
|5.||Schäfer, Heiner: 10 articles (07/2014 - 01/2009)|
|6.||Sebens, Susanne: 9 articles (01/2015 - 01/2010)|
|7.||Kiefel, Helena: 9 articles (01/2014 - 06/2009)|
|8.||Pfeifer, Marco: 9 articles (01/2013 - 01/2010)|
|9.||Zeimet, Alain G: 7 articles (11/2014 - 04/2010)|
|10.||Müller-Holzner, Elisabeth: 7 articles (11/2014 - 04/2010)|
|1.||Neoplasm Metastasis (Metastasis)
10/01/2010 - "Thus, the present study aims at further elucidating the role of L1CAM in a larger cohort of PDAC specimens including precursor lesions and metastasis. "
11/28/2014 - "L1CAM promotes cell motility, invasion, chemoresistance and metastasis formation. "
09/01/2014 - "Only for the diabetic patients (n = 34), patients with pelvic lymph node metastasis had more L1CAM expression than those without lymph node metastasis (50.0% vs. 3.6%, P = 0.035). "
09/01/2014 - "However, we failed to find any significant association between L1CAM expression and lymph node metastasis. "
09/01/2014 - "The association between L1CAM expression and pelvic lymph node metastasis was assessed according to the presence of diabetes. "
|2.||Ovarian Neoplasms (Ovarian Cancer)
11/28/2014 - "In patient cohorts from renal, endometrial and ovarian cancers we observed a strong positive correlation of L1CAM and miR-21-3p expressions. "
07/01/2012 - "Ovarian cancer cell lines were analyzed for the contribution of L1CAM to IL-1β production and nuclear factor 'kappa-light-chain-enhancer' of activated B-cells (NF-κB) activation. "
07/01/2012 - "Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-κB activation."
05/01/2009 - "Molecular genetic analysis of a cell adhesion molecule with homology to L1CAM, contactin 6, and contactin 4 candidate chromosome 3p26pter tumor suppressor genes in ovarian cancer."
12/01/2014 - "Recently, we could show that radioimmunotherapy (RIT) with (177)Lu-labelled anti-L1 cell adhesion molecule (L1CAM) monoclonal antibody chCE7 is effective in ovarian cancer therapy. "
|3.||T-Cell Lymphoma (Lymphoma, T Cell)
01/01/2014 - "In a well-established T-cell lymphoma spontaneous metastasis model, silencing of L1CAM significantly improved survival of the mice, while intradermal tumour growth remained unaltered. "
01/01/2014 - "L1CAM suppression abrogated the metastatic potential of T-cell lymphoma as well as carcinoma cells as demonstrated by reduced migration and invasion in vitro and reduced formation of experimental metastasis in vivo. "
01/01/2012 - "The aim of this study was to investigate the expression of L1CAM in HCC and determine its correlation with tumor progression and prognosis. "
01/01/2011 - "Moreover, our study is the first one describing the control of the human L1CAM promoter in tumor cells."
01/01/2010 - "Our findings suggest that the L1CAM transcriptional regulation is more complex than anticipated and this study provides the basis for a better understanding of L1CAM regulation in non-neuronal/tumor cells."
03/01/2015 - "Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT."
11/28/2014 - "Our findings shed new light on the complex regulation of L1CAM in cancers and advocate the use of L1CAM/miR-21-3p for diagnostic application. "
01/01/2014 - "In this study, we aimed to extend this finding to haematogenous malignancies and carcinomas, and to specifically elucidate the impact of L1CAM on major steps of the metastatic cascade. "
04/01/2011 - "Many studies have now shown that L1CAM is overexpressed in human carcinomas and associated with poor prognosis. "
05/01/2015 - "A significantly higher expression of ER and PR, and a lower expression of L1CAM, p53 and MLH1 were found in type I and III compared to type II carcinomas. "
11/28/2014 - "Over-expression of miR-21-3p (miR-21*) but not the complementary sequence miR-21-5p (miR-21) could strongly augment L1CAM expression in renal, endometrial and ovarian carcinoma derived cell lines by an unknown mechanism involving transcriptional activation of the L1CAM gene. "
11/28/2014 - "miR-21-3p is a positive regulator of L1CAM in several human carcinomas."
|1.||Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)
|2.||Messenger RNA (mRNA)
|6.||Cell Adhesion Molecules
|7.||Transforming Growth Factors (Transforming Growth Factor)
|8.||Extracellular Matrix Proteins
|10.||tumor-associated antigen GA733
|2.||Heterologous Transplantation (Xenotransplantation)
|5.||Drug Therapy (Chemotherapy)