|1.||Oliveras-Ferraros, Cristina: 6 articles (02/2013 - 10/2008)|
|2.||Segura-Carretero, Antonio: 6 articles (02/2013 - 10/2008)|
|3.||Menendez, Javier A: 5 articles (02/2013 - 10/2008)|
|4.||Vazquez-Martin, Alejandro: 4 articles (02/2013 - 10/2008)|
|5.||Lozano-Sánchez, Jesús: 3 articles (02/2013 - 09/2010)|
|6.||Fernández-Gutiérrez, Alberto: 3 articles (06/2011 - 01/2010)|
|7.||Joven, Jorge: 2 articles (02/2013 - 06/2011)|
|8.||Micol, Vicente: 2 articles (02/2013 - 06/2011)|
|9.||Fernández-Arroyo, Salvador: 2 articles (02/2013 - 06/2011)|
|10.||Cufí, Sílvia: 2 articles (02/2013 - 06/2011)|
01/01/2012 - "Research has confirmed that iridoids exhibit promising anti-inflammatory activity which may be beneficial in the treatment of inflammation. "
01/01/2015 - "diffusa had protective effect on renal inflammation, which possibly resulted from the bioactive constituents consisting of flavonoids, iridoids and anthraquinones. "
02/18/2000 - "The activity of the four glycoterpenoids: two saponins, verbascosaponin A and verbascosaponin, and two iridoids, scropolioside A and scrovalentinoside, isolated from Scrophularia auriculata ssp. pseudoauriculata, were studied in different models of acute and chronic inflammation. "
05/01/2015 - "In recent years, much attention has been draw to the iridoids, one of the major bioactive constituents of V. jatamansi, leading to the discovery of a series of new iridoids with anti-tumor and neuroprotective activities. "
02/15/2013 - "As such, EVOO secoiridoids constitute a new family of plant-produced gerosuppressant agents that molecularly "repair" the aimless (and harmful) AMPK/mTOR-driven quasi-program that leads to aging and aging-related diseases, including cancer."
01/01/2012 - "No single iridoid glycoside exerted any cytotoxicity in the tumor cells, whereas H-iridoids had significant cytotoxic, antiproliferative, and STAT3 inhibitory effects and revealed different potencies depending on their chemical structures. "
01/01/2012 - "The effects of several H-iridoids on cell viability and cell proliferation in tumor cells were measured by the MTT assay. "
04/19/1996 - "Among the 15 iridoids evaluated, the glycoside, paederoside, displayed the highest order of anti-tumor promoting activity."
01/01/2012 - "Studies have confirmed that extracts from Borreria and Spermacoce species as well as their isolated compounds possess diverse biological activities, including anti-inflammatory, antitumor, antimicrobial, larvicidal, antioxidant, gastrointestinal, anti-ulcer, and hepatoprotective, with alkaloids and iridoids as the major active principles. "
|4.||Breast Neoplasms (Breast Cancer)
04/01/2013 - "Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer."
06/01/2011 - "Oleaceae secoiridoids could provide a valuable phytochemical platform for the design of more pharmacologically active second-generation phytopharmaceutical anti-breast cancer molecules with a unique mode of action."
09/22/2010 - "Remarkably, breast cancer cell sensitivity to crude EVOO-PEs was up to 12 times higher in secoiridoids enriched-PE than in secoiridoids-low/null EVOO-PE."
06/01/2011 - "Secoiridoids, a family of complex polyphenols characteristic of Oleaceae plants, appear to permit histones to remain in hyperacetylated states and through the resulting alterations in gene regulation to reduce mitotic viability and metabolic competence of breast cancer cells inherently refractory to HER-targeting therapies ab initio. "
01/01/2009 - "Our current findings not only molecularly support recent epidemiological evidence revealing that EVOO-related anti-breast cancer effects primarily affect the occurrence of breast tumors over-expressing the type I receptor tyrosine kinase HER2 but further suggest that the stereochemistry of EVOO-derived lignans and secoiridoids might provide an excellent and safe platform for the design of new HER2 targeted anti-breast cancer drugs."
02/01/2002 - "As part of our screening of antiviral agents from medicinal plants, 11 compounds from plant origin (Bupleurum rigidum and Scrophularia scorodonia), three saikosaponins, seven iridoids and one phenylpropanoid glycoside were tested in vitro against herpes simplex type I (HSV-1), vesicular stomatitis virus (VSV) and poliovirus type 1. Five of these compounds showed antiviral activity against VSV. "