|1.||Lang, Charles H: 7 articles (01/2014 - 10/2004)|
|2.||Schneider, Robert J: 5 articles (03/2015 - 07/2004)|
|3.||Frost, Robert A: 5 articles (08/2007 - 10/2004)|
|4.||Wagner, Gerhard: 4 articles (08/2014 - 01/2007)|
|5.||Chorev, Michael: 4 articles (08/2014 - 01/2007)|
|6.||Halperin, Jose A: 4 articles (08/2014 - 01/2007)|
|7.||Vary, Thomas C: 4 articles (09/2007 - 02/2006)|
|8.||Aktas, Bertal H: 3 articles (08/2014 - 08/2012)|
|9.||Caranta, Carole: 3 articles (01/2010 - 01/2006)|
|10.||Carrasco, Luis: 3 articles (12/2009 - 02/2006)|
01/01/2013 - "Our previous studies demonstrate these selective anti-cancer effects of Reishi, where IBC cell viability and invasion, as well as the expression of key IBC molecules, including eIF4G is compromised. "
01/01/2014 - "In humans, aberrant expression of eIF4G is associated with certain forms of cancer and neurodegeneration. "
05/13/2011 - "Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor."
11/09/2007 - "Using model animal and cell studies, we then show that overexpressed 4E-BP1 and eIF4G orchestrate a hypoxia-activated switch from cap-dependent to cap-independent mRNA translation that promotes increased tumor angiogenesis and growth at the level of selective mRNA translation. "
08/05/2014 - "Indeed, we discovered small-molecule inhibitors of this eIF4E/eIF4G interaction (4EGIs) that inhibit translation initiation both in vitro and in vivo and were used successfully in numerous cancer-biology and neurobiology studies. "
05/01/2010 - "Cleavage of eIF4G occurs upon poliovirus infection and is responsible for the shut-off of host-cell protein synthesis observed early in infection. "
03/06/2007 - "The colonization pattern by a viral recombinant carrying GFP indicated that eIF4G is involved at a very early infection step. "
03/06/2007 - "Susceptibility analyses of Arabidopsis mutants knocked-out for At-eIF4G genes showed that eIF4G factors are indispensable for potyvirus infection. "
05/01/2006 - "CBV infection resulted in efficient cleavage of eIF4G and PABP, coincident with polyribosome breakdown in the cytosol and ER compartments. "
02/03/2006 - "Viral protein synthesis at late times of infection by the recombinant viruses is slightly affected in BHK cells that contain proteolysed eIF4G. "
12/01/2006 - "Taken together, the data indicate that a cytokine-dependent decrease in the steady state phosphorylation of eIF4G is a possible mechanism accounting for the inhibition of skeletal muscle protein synthesis during sepsis. "
12/01/2006 - "To examine the mediators of the septic process contributing to the decreased levels of phosphorylated eIF4G, the cytokine response to sepsis was pharmacologically modulated. "
12/01/2006 - "Cytokine-triggered decreases in levels of phosphorylated eukaryotic initiation factor 4G in skeletal muscle during sepsis."
01/01/2014 - "Sepsis decreased the binding of eIF4G to eIF4E in WT mice; however, eIF4E•eIF4G binding was not altered in DKO mice under either basal or septic conditions. "
09/01/2007 - "We conclude that Leu stimulates a PKB-independent signal pathway elevating the eIF4G-eIF4E complex assembly through increased phosphorylation of eIF4G and decreased association of 4E-BP1 with eIF4E in skeletal muscle during sepsis."
01/01/2009 - "In the studies reported here, in addition to heat shock, we have included results of our investigation on the association between eIF4G, PABP1 and HSP27 during recovery from heat shock, when cap-dependent mRNA translation resumes. "
01/01/2009 - "Therefore, our results raise the possibility that the association of HSP27 with eIF4G may not be sufficient to suppress cap-dependent translation during heat shock. "
01/01/2009 - "During recovery after heat shock, PABP1 and eIF4G were redistributed into the cytoplasm and colocalized with each other. "
06/15/2000 - "Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes."
04/01/1999 - "These findings indicate that intact eIF4G is necessary for the translation of mRNAs not engaged in translation with the exception of heat shock mRNAs but is not necessary for the translation of mRNAs that are being translated."
02/14/2012 - "Phosphorylation of Ser¹¹⁰⁸ in eIF4G, in gastrocnemius muscle, was increased in mice lacking MNK2, but not those lacking MNK1, and this increased phosphorylation was maintained in MNK2-null animals under atrophy conditions and upon starvation. "
05/01/1997 - "Starvation and refeeding also altered the amount of eIF-4G that coimmunoprecipitated with eIF-4E. "
07/06/2011 - "We demonstrate that knockdown of eukaryotic translation initiation factor 4G (eIF4G), which is downregulated during starvation and dauer state, results in differential translation of genes important for growth and longevity in C. elegans. "
08/01/2002 - "In addition, Ypk1 as well as eIF4G protein levels were rapidly depleted upon nitrogen starvation, but not during glucose starvation, even though both conditions inhibit translation initiation. "
05/01/1997 - "The alterations in 4E-BP1 phosphorylation and association of 4E-BP1 and eIF-4G with eIF-4E observed in control mice in response to starvation and refeeding were also observed in diabetic mice exhibiting characteristics of type I or type II diabetes subjected to the same conditions, suggesting that insulin alone does not mediate the observed changes. "
|1.||Eukaryotic Initiation Factor-4E
|2.||Peptide Initiation Factors (Initiation Factor)
|3.||Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)
|4.||Eukaryotic Initiation Factor-4F (EIF4F)
|5.||Messenger RNA (mRNA)
|6.||Protein Isoforms (Isoforms)
|9.||70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Induced Heart Arrest (Cardioplegia)