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Integrin alphaV

An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.
Also Known As:
CD51 Antigen; Integrin alpha V; alpha(V) Integrin; alphav Integrin; Antigen, CD51; Integrin, alphav; alpha V, Integrin; alphaV, Integrin; Antigens, CD51; CD51 Antigens
Networked: 260 relevant articles (7 outcomes, 25 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chen, Xiaoyuan: 10 articles (05/2008 - 01/2004)
2. Bading, James R: 6 articles (01/2006 - 01/2004)
3. Conti, Peter S: 6 articles (01/2006 - 01/2004)
4. Park, Ryan: 6 articles (01/2006 - 01/2004)
5. Tohme, Michel: 6 articles (01/2006 - 01/2004)
6. Sheppard, Dean: 5 articles (01/2008 - 01/2002)
7. Hou, Yingping: 5 articles (03/2005 - 08/2004)
8. McCarty, Joseph H: 4 articles (07/2011 - 11/2002)
9. Carreiras, Franck: 4 articles (04/2010 - 01/2002)
10. Huang, Xiaozhu: 4 articles (06/2008 - 01/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Neoplasm Metastasis (Metastasis)
4. Melanoma (Melanoma, Malignant)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. arginyl-glycyl-aspartic acid
2. Ligands
3. Peptides (Polypeptides)
4. Integrin alphaVbeta3
5. Monoclonal Antibodies
6. intetumumab
7. Small Interfering RNA (siRNA)
8. Angiogenesis Inhibitors
9. Doxorubicin (Adriamycin)
10. NGR peptide

Related Therapies and Procedures

1. Radiotherapy
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Ligation
5. Microbubbles