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Non-Sedating Histamine H1 Antagonists (Histamine H1 Antagonists, Non Sedating)

A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.
Also Known As:
Histamine H1 Antagonists, Non Sedating; Histamine H1 Antagonists, Non-Sedating; H1 Antihistamines, Non-Sedating; Second Generation Antihistamines; Second Generation H1 Antagonists; Third Generation H1 Antagonists; Antihistamines, Second Generation; H1 Antihistamines, Non Sedating; Non-Sedating H1 Antihistamines
Networked: 96 relevant articles (26 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Okubo, Kimihiro: 2 articles (11/2015 - 09/2006)
2. Ortonne, Jean-Paul: 2 articles (01/2012 - 12/2011)
3. Bachert, Claus: 2 articles (11/2011 - 05/2009)
4. Maurer, Marcus: 2 articles (04/2010 - 10/2008)
5. Meyer, Kellie: 2 articles (11/2009 - 10/2008)
6. Kaliner, Michael A: 2 articles (11/2009 - 06/2009)
7. Goodman, Michael J: 2 articles (11/2009 - 10/2008)
8. Jhaveri, Mehul: 2 articles (11/2009 - 10/2008)
9. Hay, Joel W: 2 articles (06/2009 - 07/2005)
10. Soma, Yoshinao: 2 articles (08/2006 - 10/2003)

Related Diseases

1. Rhinitis
2. Urticaria (Hives)
3. Pruritus (Itching)
4. Inflammation
5. Hypersensitivity (Allergy)

Related Drugs and Biologics

1. Histamine Antagonists (Antihistamines)
2. Loratadine (Alavert)
3. Adrenal Cortex Hormones (Corticosteroids)
4. Histamine (Histamine Dihydrochloride)
5. Astemizole
6. ebastine (Kestin)
7. olopatadine (Patanol)
8. Cetirizine (Zyrtec)
9. Terfenadine (Seldane)
10. montelukast (Singulair)

Related Therapies and Procedures

1. Condoms (Condom)
2. Drug Therapy (Chemotherapy)