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Eukaryotic Initiation Factor-4F (EIF4F)

A trimeric peptide initiation factor complex that associates with the 5' MRNA cap structure of RNA (RNA CAPS) and plays an essential role in MRNA TRANSLATION. It is composed of EUKARYOTIC INITIATION FACTOR-4A; EUKARYOTIC INITIATION FACTOR-4E; and EUKARYOTIC INITIATION FACTOR-4G.
Also Known As:
EIF4F; EIF-(iso)4F; EIF4F Translation Initiation Complex; Eukaryotic Initiation Factor-(iso)4F; Protein Initiation Factor EIF-4F; EIF 4F; Eukaryotic Initiation Factor 4F; Initiation Factor-4F, Eukaryotic; Peptide Initiation Factor EIF 4F; Protein Initiation Factor EIF 4F; EIF-4F; Peptide Initiation Factor EIF-4F
Networked: 96 relevant articles (0 outcomes, 9 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Pelletier, Jerry: 8 articles (04/2015 - 10/2009)
2. Bitterman, Peter B: 5 articles (07/2015 - 06/2004)
3. Sonenberg, Nahum: 5 articles (04/2015 - 06/2004)
4. Walsh, Derek: 5 articles (01/2011 - 03/2004)
5. Polunovsky, Vitaly A: 4 articles (07/2015 - 06/2004)
6. Mohr, Ian: 4 articles (01/2011 - 03/2004)
7. Tillu, Dipti V: 3 articles (05/2015 - 11/2010)
8. Price, Theodore J: 3 articles (05/2015 - 11/2010)
9. Kratzke, Robert A: 3 articles (08/2014 - 03/2011)
10. Patel, Manish R: 3 articles (08/2014 - 03/2011)

Related Diseases

1. Infection
2. Mesothelioma
3. Neoplasms (Cancer)
4. Lymphoma (Lymphomas)
5. Multiple Myeloma

Related Drugs and Biologics

1. Eukaryotic Initiation Factor-4E
2. Peptide Initiation Factors (Initiation Factor)
3. Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)
4. RNA Cap-Binding Proteins (Cap Binding Protein)
5. MicroRNAs (MicroRNA)
6. Proteome
7. Protein Isoforms (Isoforms)
8. Transcription Factors (Transcription Factor)
9. cetuximab (Erbitux)
10. erlotinib (CP 358,774)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Therapeutics
3. Drug Therapy (Chemotherapy)