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Eukaryotic Initiation Factor-4E

A peptide initiation factor that binds specifically to the 5' MRNA CAP STRUCTURE of MRNA in the CYTOPLASM. It is a component of the trimeric complex EIF4F.
Also Known As:
CDC33 Gene Product; EIF4E; Eukaryotic Peptide Initiation Factor-4E; EIF 4E; Eukaryotic Initiation Factor 4E; Eukaryotic Peptide Initiation Factor 4E; Factor-4E, Eukaryotic Initiation; Initiation Factor-4E, Eukaryotic; Peptide Initiation Factor EIF 4E; EIF-4E; Peptide Initiation Factor EIF-4E
Networked: 567 relevant articles (5 outcomes, 83 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Borden, Katherine L B: 23 articles (01/2015 - 03/2002)
2. Sonenberg, Nahum: 19 articles (10/2015 - 04/2004)
3. Pelletier, Jerry: 12 articles (09/2014 - 03/2004)
4. Li, Benjamin D L: 12 articles (10/2009 - 05/2002)
5. Topisirovic, Ivan: 11 articles (05/2015 - 09/2002)
6. Kimball, Scot R: 10 articles (11/2015 - 09/2005)
7. Bitterman, Peter B: 10 articles (07/2015 - 05/2004)
8. Graff, Jeremy R: 10 articles (05/2013 - 01/2003)
9. Meschonat, Carol: 9 articles (10/2009 - 01/2004)
10. Fukunaga, Rikiro: 8 articles (06/2015 - 11/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
4. Prostatic Neoplasms (Prostate Cancer)
5. Disease Progression

Related Drugs and Biologics

1. gemcitabine
2. eIF-4B
3. Peptide Initiation Factors (Initiation Factor)
4. Eukaryotic Initiation Factor-4E
5. Sirolimus (Rapamycin)
6. Proteins (Proteins, Gene)
7. Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)
8. Messenger RNA (mRNA)
9. Eukaryotic Initiation Factor-4F (EIF4F)
10. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Chemoprevention
3. Brachytherapy
4. Drug Therapy (Chemotherapy)
5. Therapeutics