|1.||Cress, Anne E: 8 articles (06/2009 - 05/2002)|
|2.||Demetriou, Manolis C: 6 articles (02/2008 - 01/2004)|
|3.||Nagle, Raymond B: 4 articles (01/2008 - 05/2002)|
|4.||Funahashi, Hitoshi: 4 articles (06/2007 - 11/2005)|
|5.||Manabe, Tadao: 4 articles (06/2007 - 11/2005)|
|6.||Sawai, Hirozumi: 4 articles (06/2007 - 11/2005)|
|7.||Takeyama, Hiromitsu: 4 articles (06/2007 - 11/2005)|
|8.||Pawar, Sangita C: 3 articles (01/2008 - 04/2007)|
|9.||Okada, Yuji: 3 articles (06/2007 - 11/2005)|
|10.||Matsuo, Yoichi: 3 articles (06/2007 - 11/2005)|
09/01/2002 - "Recent evidence suggests a pathophysiologic role for antibodies against human alpha6 integrin in blister formation in OP, in organ culture studies. "
06/01/2005 - "Recent evidence suggests a pathophysiological role for autoantibodies against alpha6 integrin in the subepidermal blister formation of oral pemphigoid. "
08/01/2008 - "Recent studies have shown that SM alkylation causes a significant reduction of laminin-5, disruption of alpha6beta4 integrin and decreases the expression of integrin alpha6 and beta4 subunits, therefore, leads to destabilization of dermal-epidermal attachments and potentiates vesication. "
02/01/1999 - "By indirect immunofluorescence using antibodies specific for alpha 6 integrin, laminin 5, type IV collagen, and type VII collagen, all of these basement membrane components were detected as coarse granular intracytoplasmic deposits only in the basal and suprabasal cells of the blister roof. "
|2.||Bullous Pemphigoid (Pemphigoid)
02/01/2006 - "Controls were sera samples from 10 healthy volunteers and 40 patients with other variants of mucous membrane pemphigoid and mAb GoH3 and BQ16 to integrin alpha6. "
08/01/2001 - "Sera of oral pemphigoid patients selectively and specifically bound to human alpha6 integrin, a 120-kDa protein present in gingiva and the tumor cell line. "
07/01/2006 - "Previous studies have shown that sera of patients with MMP bind to human integrin beta4, while sera of patients with oral pemphigoid bind to the integrin alpha6 component of the heterodimer. "
07/01/1995 - "Molecular genetic studies of a human epidermal autoantigen (the 180-kD bullous pemphigoid antigen/BP180): identification of functionally important sequences within the BP180 molecule and evidence for an interaction between BP180 and alpha 6 integrin."
09/01/2007 - "The binding of BP180 with either integrin alpha6, integrin beta4, or bullous pemphigoid antigen-1 (BPAG1/BP230) is critical for this attachment in skin. "
05/07/2010 - "Targeting integrin alpha6 in GSCs inhibits self-renewal, proliferation, and tumor formation capacity. "
04/01/2010 - "TAF4b and Jun/activating protein-1 collaborate to regulate the expression of integrin alpha6 and cancer cell migration properties."
06/15/2009 - "Validation of the alpha(6) cleavage effect on extravasation was confirmed through a genetic approach using tumor cells transfected with uncleavable alpha(6) integrin. "
11/01/2007 - "The tumor response to IR was altered in tumors expressing the mutant alpha6 integrin as indicated by a significant increase in tumor growth inhibition, an increase in tumor growth delay, an increase in tumor doubling time and an increase in tumor cell kill. "
11/01/2007 - "The goal was to determine if prostate tumor cells containing a mutant alpha6 integrin would be defective in tumor re-population following clinically relevant fractionated ionizing radiation (IR) treatments. "
02/15/1995 - "In the current study, we investigated the expression of human alpha 6 integrin in invasive breast carcinomas of 119 women. "
01/01/2010 - "Thrombospondin-1 (TSP-1) Stimulates Expression of Integrin alpha6 in Human Breast Carcinoma Cells: A Downstream Modulator of TSP-1-Induced Cellular Adhesion."
06/15/2009 - "We show that alpha(6) integrin was present on prostate carcinoma escaping the gland via nerves. "
04/01/2000 - "To our knowledge, however, there are no reports on alpha6 integrin expression in esophageal carcinoma. "
04/01/2000 - "alpha6 integrin expression in esophageal carcinoma."
|5.||Prostatic Neoplasms (Prostate Cancer)
05/15/2012 - "A number of putative stem cell markers have been associated with aggressiveness of prostate cancer, including alpha 2 and alpha 6 integrin and c-met. "
02/15/2008 - "We have previously reported a uPA cleaved form of integrin alpha6 (alpha6p), in invasive human prostate cancer tissue, whose presence correlates with increased migration and invasive capacity. "
11/01/2007 - "Human prostate cancer cells derived from PC3N cells were used which conditionally expressed a cleavable, wild type form of alpha6 integrin (PC3N-alpha6-WT) or a mutated non-cleavable form of alpha6 integrin (PC3N-alpha6-RR). "
11/01/2007 - "alpha6 integrin cleavage: sensitizing human prostate cancer to ionizing radiation."
04/01/2007 - "Prostate cancer cells (PC3N) were stably transfected to overexpress the cleavable, wild-type (PC3N-alpha6-WT) or the non-cleavable form of integrin alpha6 (PC3N-alpha6-RR). "
|4.||Messenger RNA (mRNA)
|9.||Collagen Type VII
|10.||Focal Adhesion Protein-Tyrosine Kinases
|1.||Heterologous Transplantation (Xenotransplantation)