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Integrin alpha6beta4

This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
Also Known As:
A9 Antigen; Integrin alpha(6),beta(4); Laminin-5 Receptor (alpha6beta4 Integrin); TSP-180; Tumor Specific Protein-180 Complex; alpha(6)beta(4) Epithelial Integrin; alpha(6)beta(4) Integrin; alpha6 beta4 Integrin; Antigen, A9; Integrin, alpha6 beta4; Tumor Specific Protein 180 Complex; alpha6beta4, Integrin; beta4 Integrin, alpha6
Networked: 210 relevant articles (1 outcomes, 23 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Mercurio, Arthur M: 10 articles (02/2007 - 07/2002)
2. Chung, Jun: 6 articles (10/2009 - 07/2002)
3. Lipscomb, Elizabeth A: 6 articles (03/2006 - 07/2002)
4. Folgiero, Valentina: 5 articles (07/2009 - 06/2006)
5. Sacchi, Ada: 5 articles (07/2009 - 06/2006)
6. Bon, Giulia: 5 articles (07/2009 - 06/2006)
7. Falcioni, Rita: 5 articles (07/2009 - 06/2006)
8. Zhou, Xiao: 5 articles (01/2009 - 02/2004)
9. Gilcrease, Michael Z: 5 articles (01/2009 - 02/2004)
10. Falzon, Miriam: 4 articles (07/2009 - 11/2006)

Related Diseases

1. Blister (Bulla)
2. Neoplasms (Cancer)
3. Carcinoma (Carcinomatosis)
4. Breast Neoplasms (Breast Cancer)
5. Bullous Pemphigoid (Pemphigoid)

Related Drugs and Biologics

1. kalinin
2. Integrin alpha6
3. Antigens
4. Blood Group Antigens (Blood Groups)
5. Laminin Receptors
6. laminin 1
7. Phosphotransferases (Kinase)
8. Monoclonal Antibodies
9. Complementary DNA (cDNA)
10. Tyrosine (L-Tyrosine)

Related Therapies and Procedures

1. Ligation
2. Heterologous Transplantation (Xenotransplantation)
3. Traction
4. Immunotherapy