Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.
Also Known As:
VLA-4; CD49d-CD29; Integrin Heterodimer alpha4beta1; Integrin alpha(4)beta(1); Very Late Activation Antigen-4; Very Late Antigen-4; alpha4beta1 Integrin; Antigen-4, Very Late; Heterodimer alpha4beta1, Integrin; Integrin, alpha4beta1; Late Antigen-4, Very; Very Late Activation Antigen 4; Very Late Antigen 4; alpha4beta1, Integrin; alpha4beta1, Integrin Heterodimer