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70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)

A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.
Also Known As:
Ribosomal Protein S6 Kinases, 70 kDa; p70s6k; Ribosomal Protein S6 Kinases, 70-kDa; S6 Kinase, p70; p70 S6 Kinase
Networked: 454 relevant articles (13 outcomes, 52 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wu, Miaozong: 6 articles (01/2012 - 01/2009)
2. Katta, Anjaiah: 6 articles (01/2012 - 01/2009)
3. Pei, Jin-Jing: 6 articles (11/2008 - 08/2003)
4. Maiese, Kenneth: 5 articles (12/2014 - 01/2012)
5. Paturi, Satyanarayana: 5 articles (01/2012 - 01/2009)
6. Blough, Eric R: 5 articles (01/2012 - 01/2009)
7. Winblad, Bengt: 5 articles (11/2008 - 08/2003)
8. Yellon, Derek M: 5 articles (08/2007 - 09/2003)
9. Patsouris, Efstratios: 4 articles (08/2015 - 01/2010)
10. Ding, Ke: 4 articles (07/2015 - 07/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Melanoma (Melanoma, Malignant)
3. Tuberous Sclerosis (Bourneville's Disease)
4. Lymphangioleiomyomatosis (Lymphangiomyomatosis)
5. Parkinson Disease (Parkinson's Disease)

Related Drugs and Biologics

1. Sirolimus (Rapamycin)
2. Ribosomal Protein S6 Kinases (S6 Kinase)
3. Curcumin
4. Quercetin
5. everolimus
6. Proto-Oncogene Proteins c-akt (Protein Kinase B)
7. Glucose (Dextrose)
8. Proline (L-Proline)
9. Synucleins
10. Isoflurane

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Ischemic Postconditioning
4. Resistance Training
5. Aftercare (After-Treatment)