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90-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 90 kDa)

A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN.
Also Known As:
Ribosomal Protein S6 Kinases, 90 kDa; Ribosomal Protein S6 Kinases, 90-kDa; MAPKAP Kinase-1; MAPKAP-K1; MAPKAPK1; Ribosomal Protein S6 Kinase, 90-kDa; p90 Ribosomal S6 Kinase; p90(rsk); pp90(rsk); MAP Kinase Activated Kinase 1; MAP Kinase Activated Protein Kinase 1; MAPKAP Kinase 1; Ribosomal Protein S6 Kinase, 90 kDa; MAP-Kinase-Activated Kinase 1; MAP-Kinase-Activated Protein Kinase 1
Networked: 60 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Roux, Philippe P: 4 articles (07/2014 - 09/2004)
2. Taunton, Jack: 4 articles (11/2013 - 08/2008)
3. Blenis, John: 3 articles (07/2014 - 09/2004)
4. Ballif, Bryan A: 3 articles (07/2014 - 09/2004)
5. Dunn, Sandra E: 3 articles (01/2014 - 01/2008)
6. Berk, Bradford C: 3 articles (08/2011 - 01/2002)
7. Abe, Jun-ichi: 3 articles (08/2008 - 01/2002)
8. Appleton, Brent A: 2 articles (09/2015 - 05/2014)
9. Jefferson, Anne B: 2 articles (09/2015 - 05/2014)
10. Lan, Jiong: 2 articles (09/2015 - 05/2014)

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Ischemia
3. Acidosis
4. Insulin Resistance
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. Ribosomal Protein S6 Kinases (S6 Kinase)
3. Mitogen-Activated Protein Kinase 7
4. 70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)
5. Small Interfering RNA (siRNA)
6. Muscle Proteins (Muscle Protein)
7. Protein Kinases (Protein Kinase)
8. Mitogen-Activated Protein Kinase 3
9. 90-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 90 kDa)
10. Sodium-Hydrogen Antiporter